2. Gene
  3. Rps6kb1 - ribosomal protein S6 kinase, polypeptide 1 Gene

Rps6kb1 - ribosomal protein S6 kinase, polypeptide 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as S6K; S6K1; p70s6k; P70S6K1; p70 S6KA; p70-S6K 1; p70/85s6k; S6K-beta-1; 2610318I15Rik; p70 S6K-alpha

Gene ID: 72508 | Gene type: protein coding

About Rps6kb1

Chromosome 11: 86,389,697-86,435,631 reverse strand.GRCm39:CM001004.3

This gene has 7 transcripts (splice variants), 155 orthologues, 7 paralogues and is associated with 25 phenotypes. Ubiquitous expression in CNS E11.5 (RPKM 5.), limb E14.5 (RPKM 4.8) and 26 other tissues.

Summary

Enables protein kinase activity. Involved in several processes, including cellular response to interferon-gamma; long-chain fatty acid import into cell; and peptidyl-serine phosphorylation. Acts upstream of or within several processes, including behavioral fear response; cellular response to hormone stimulus; and protein kinase B signaling. Located in mitochondrion. Is expressed in several structures, including central nervous system; early conceptus; olfactory epithelium; reproductive system; and retina nuclear layer. Orthologous to human RPS6KB1 (ribosomal protein S6 kinase B1). [provided by Alliance of Genome Resources, Apr 2022]

Rps6kb1 Products(3)

mRNA Protein Name
NM_001363162.1 NP_001350091.1 ribosomal protein S6 kinase beta-1 isoform 3
NM_028259.4 NP_082535.1 ribosomal protein S6 kinase beta-1 isoform 2
NM_001114334.2 NP_001107806.1 ribosomal protein S6 kinase beta-1 isoform 1

Rps6kb1 Protein Structure

STKc_p70S6K

STKc_p70S6K: cd05584 (93 - 415)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 525 a.a.
Protein Preferred Names Protein Names

ribosomal protein S6 kinase beta-1

70 kDa ribosomal protein S6 kinase 1

p70 S6 kinase alpha

p70 ribosomal S6 kinase alpha

ribosomal protein S6 kinase I

ribosomal protein S6 kinase, 70kD, polypeptide 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148062 RSS0680 98.03% Unkown
HY-RS12262 RPS6KB1 Human Pre-designed siRNA Set A / Unkown
HY-RS12263 Rps6kb1 Mouse Pre-designed siRNA Set A / Unkown
HY-RS12264 Rps6kb1 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rps6kb1 NCBI NCBI:6198