RPS6KB1 - ribosomal protein S6 kinase B1 Gene

Also Known as S6K; PS6K; S6K1; STK14A; p70-S6K; p70 S6KA; p70-alpha; S6K-beta-1; p70(S6K)-alpha

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 6198

About RPS6KB1

Cytogenetic location: 17q23.1 Genomic coordinates (GRCh38): 17:59,893,121-59,950,574 (from NCBI)

This gene has 12 transcripts (splice variants), 156 orthologues and 7 paralogues. Ubiquitous expression in esophagus (RPKM 6.9), thyroid (RPKM 6.8) and 25 other tissues.

Summary

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human Cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]

RPS6KB1 Products (25)

mRNA Protein Name
NM_001369679.1 NP_001356608.1 ribosomal protein S6 kinase beta-1 isoform l
NR_161458.1
NR_161456.1
NR_161460.1
XM_011525102.4 XP_011523404.1 ribosomal protein S6 kinase beta-1 isoform X1
NM_001272043.2 NP_001258972.1 ribosomal protein S6 kinase beta-1 isoform c
NM_001272042.2 NP_001258971.1 ribosomal protein S6 kinase beta-1 isoform b
NR_161455.1
NM_003161.4 NP_003152.1 ribosomal protein S6 kinase beta-1 isoform a
NM_001272044.2 NP_001258973.1 ribosomal protein S6 kinase beta-1 isoform d
NM_001369676.1 NP_001356605.1 ribosomal protein S6 kinase beta-1 isoform l
NM_001369669.1 NP_001356598.1 ribosomal protein S6 kinase beta-1 isoform f
NM_001369672.1 NP_001356601.1 ribosomal protein S6 kinase beta-1 isoform i
NM_001369677.1 NP_001356606.1 ribosomal protein S6 kinase beta-1 isoform l
NM_001369678.1 NP_001356607.1 ribosomal protein S6 kinase beta-1 isoform l
NM_001272060.2 NP_001258989.1 ribosomal protein S6 kinase beta-1 isoform e
NM_001369674.1 NP_001356603.1 ribosomal protein S6 kinase beta-1 isoform k
NR_161459.1
NM_001369671.1 NP_001356600.1 ribosomal protein S6 kinase beta-1 isoform h
NR_161462.1
NR_161461.1
NM_001369675.1 NP_001356604.1 ribosomal protein S6 kinase beta-1 isoform k
NM_001369673.1 NP_001356602.1 ribosomal protein S6 kinase beta-1 isoform j
NM_001369670.1 NP_001356599.1 ribosomal protein S6 kinase beta-1 isoform g
NR_161457.1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11438723 GOA
enables protein kinase activity IDA
IDA: Inferred from direct assay
17936702 GOA
enables protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
1922062 GOA
enables protein serine/threonine/tyrosine kinase activity IDA
IDA: Inferred from direct assay
22797923 GOA
Biological Process GO Annotation Evidence References Source
involved in G1/S transition of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
14673156 GOA
involved in TOR signaling IDA
IDA: Inferred from direct assay
12150926 GOA
involved in TOR signaling IMP
IMP: Inferred from mutant phenotype
28178239 GOA
involved in cellular response to growth factor stimulus IDA
IDA: Inferred from direct assay
17936702 GOA
involved in cellular response to nutrient IDA
IDA: Inferred from direct assay
22017876 GOA
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
17936702 GOA
involved in negative regulation of insulin receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
18952604 GOA
involved in peptidyl-serine phosphorylation IMP
IMP: Inferred from mutant phenotype
28178239 GOA
involved in positive regulation of TORC1 signaling IDA
IDA: Inferred from direct assay
22017876 GOA
involved in positive regulation of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
14673156 GOA
involved in positive regulation of translation IMP
IMP: Inferred from mutant phenotype
18423201 GOA
involved in positive regulation of translational initiation IDA
IDA: Inferred from direct assay
1922062 GOA
involved in positive regulation of translational initiation IMP
IMP: Inferred from mutant phenotype
16763566 GOA
involved in response to nutrient levels IDA
IDA: Inferred from direct assay
29750193 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
19085255 GOA
located in mitochondrion IDA
IDA: Inferred from direct assay
17936702 GOA
located in nucleus IDA
IDA: Inferred from direct assay
19085255 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RPS6KB1 Protein Structure

Pkinase

Pkinase: Protein kinase domain (91 - 352)

Pkinase_C

Pkinase_C: Protein kinase C terminal domain (374 - 417)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 525 a.a.
Protein Preferred Names Protein Names

ribosomal protein S6 kinase beta-1

  • ribosomal protein S6 kinase I

  • ribosomal protein S6 kinase, 70kDa, polypeptide 1

  • serine/threonine kinase 14 alpha

  • serine/threonine-protein kinase 14A

Recombinant RPS6KB1 Proteins

Cat. No. Product Name Accession Purity
HY-P76588 S6K1/RPS6KB1 Protein, Human (Inactive, sf9, GST) P23443-1 (M1-L525) ≥ 90%, as determined by reducing SDS-PAGE.

RPS6KB1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P810610 Phospho-p70 S6 Kinase (Ser434) Antibody (YA9872) WB, IP, IF-Tissue, ICC/IF, IP Human, Mouse, Rat
HY-P811554 Phospho-p70 S6 Kinase (Ser434) Antibody WB, IHC-P, ICC/IF Human, Mouse, Rat
HY-P81209 S6K1 Antibody (YA7740) WB, ELISA, IHC-P, IHC-F, ICC/IF Human, Rat
HY-P81209A S6K1 Antibody (YA7740)(PBS only) WB, ELISA, IHC-P, IHC-F, ICC/IF Human, Rat
HY-P85754 S6K1 Antibody (YA5446) IHC-P, ICC/IF Human, Rat, Mouse
HY-P86528 S6K1 Antibody (YA6220) WB, IHC-P, ICC/IF, IP, ELISA Human, Mouse, Rat
HY-P87259 Phospho-p70 S6 Kinase (T389) Antibody (YA6944) WB, IHC-P, ICC/IF Human, Mouse, Rat

Related Diseases

Diseases Alias
Alzheimer Disease, Familial, 1

  • Alzheimer Disease

  • Alzheimer'S Disease

  • Presenile And Senile Dementia

  • AD1

  • Alzheimer Disease, Susceptibility To

  • Alzheimer Disease, Late-Onset, Susceptibility To

  • Alzheimer Disease 1, Familial

  • AD

  • Familial Alzheimer Disease

  • Alzheimer Disease, Late-Onset

  • Alzheimers Dementia

  • Alzheimer Dementia

  • Alzheimer Sclerosis

  • Alzheimer Syndrome

  • Alzheimer-Type Dementia

  • Dat

  • Primary Senile Degenerative Dementia

  • Sdat

  • Alzheimer Disease 1

  • Autosomal Dominant Alzheimer Disease

  • Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy

  • Late Onset Alzheimer Disease

  • Alzheimers Disease

  • Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy

  • Late-Onset Alzheimers Disease

  • Alzheimer'S Disease Pathway Kegg

  • Dementia Due To Alzheimer'S Disease

  • Alzheimer Disease Type 1

  • Alzheimers
Uterus Perivascular Epithelioid Cell Tumor

  • Uterine Corpus Pecoma
Spotted Fever

  • Spotted Fevers

  • Spotted Fever Group Rickettsial Disease

  • Tick-Borne Rickettsioses

  • Tick-Borne Typhus Nos

  • Rocky Mountain Spotted Fever

  • Sao Paulo Fever

  • Sao Paulo Typhus

  • Lone Star Spotted Fever

  • Colombian Spotted Fever

  • American Spotted Fever

  • Tick Typhus Due To Rickettsia Rickettsii

  • Rocky Mountain Tick Fever

  • Boutonneuse Fever

  • Mediterranean Tick Fever

  • Fièvre Boutonneuse

  • Mediterranean Spotted Fever

  • Tick Typhus Due To Rickettsia Conorii

  • African Tick Typhus

  • Indian Tick Typhus

  • Kenya Tick Typhus

  • North Asian Tick Fever

  • Siberian Tick Typhus

  • Tick Typhus Due To Rickettsia Siberica

  • North Asian Spotted Fever

  • Queensland Tick Typhus

  • Queensland Fever
Type 2 Diabetes Mellitus

  • Insulin Resistance

  • NIDDM

  • Diabetes Mellitus, Non-Insulin-Dependent

  • Type 2 Diabetes

  • T2D

  • Noninsulin-Dependent Diabetes Mellitus

  • Diabetes Mellitus, Type Ii

  • Maturity-Onset Diabetes

  • Insulin Resistance, Severe, Digenic

  • Diabetes Mellitus, Type 2

  • Diabetes Mellitus, Noninsulin-Dependent

  • Diabetes Mellitus, Noninsulin-Dependent, Association With

  • Diabetes Mellitus, Noninsulin-Dependent, Late Onset

  • Hypertension, Insulin Resistance-Related, Susceptibility To

  • Insulin Resistance, Susceptibility To

  • Non-Insulin-Dependent Diabetes Mellitus

  • Type Ii Diabetes Mellitus

  • Adult-Onset Diabetes Mellitus

  • Maturity-Onset Diabetes Mellitus

  • Diabetes Mellitus Type 2

  • Type Ii Diabetes

  • Type 2 Diabetes Mellitus, Susceptibility To

  • Diabetes, Type 2

  • Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To

  • Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To

  • Diabetes Mellitus, Type 2, Susceptibility To

  • Diabetes Mellitus, Noninsulin-Dependent, 2

  • Diabetes Mellitus, Type Ii, Susceptibility To

  • Hypertension, Insulin Resistance-Related

  • Adult-Onset Diabetes

  • Aodm

  • Diabetes Mellitus, Adult-Onset

  • Diabetes Mellitus Type Ii

  • Diabetes Mellitus Type 2, Susceptibility To

  • Diabetes, Type Ii, Susceptibility To

  • Diabetes Type 2

  • Diabetes Mellitus

  • Adult Onset Diabetes

  • Maturity Onset Diabetes

  • Nonketotic Diabetes

  • Non-Insulin Dependent Diabetes Mellitus

  • T2dm - [Type 2 Diabetes Mellitus]

  • Niddm - [Non Insulin Dependent Diabetes Mellitus]

  • Dm2

  • Dm Type Ii

  • Diabetic Type 2

  • Insulin Requiring Type 2 Diabetes

  • Noninsulin Dependent Diabetes

  • Non-Insulin-Dependent Diabetes Mellitus Without Complications

  • Diabetes Due To Insulin Secretory Defect

  • Diabetes Mellitus Due To Insulin Secretory Defect

  • Non-Insulin-Dependent Diabetes Of The Young

  • Senile Diabetes

  • Nonketotic Hyperglycaemia

  • Stable Diabetes
Kidney Angiomyolipoma

  • Angiomyolipoma Of Kidney

  • Renal Angiomyolipoma
Cowden Syndrome 1

  • Pten Hamartoma Tumor Syndrome

  • Bannayan-Riley-Ruvalcaba Syndrome

  • Lhermitte-Duclos Disease

  • Bannayan-Zonana Syndrome

  • Phts

  • Riley-Smith Syndrome

  • Bzs

  • Ruvalcaba-Myhre-Smith Syndrome

  • Multiple Hamartoma Syndrome

  • Rmss

  • Brrs

  • Dysplastic Gangliocytoma Of The Cerebellum

  • CWS1

  • Cs

  • Cd

  • Mham

  • Pten Hamartoma Tumor Syndrome With Granular Cell Tumor

  • Macrocephaly Multiple Lipomas And Hemangiomata

  • Bannayan-Ruvalcaba-Riley Syndrome

  • Myhre-Riley-Smith Syndrome

  • LDD

  • Cerebelloparenchymal Disorder Vi

  • Hamartoma Syndrome, Multiple

  • Bbrs

  • Macrocephaly, Pseudopapilledema, And Multiple Hemangiomata

  • Macrocephaly, Multiple Lipomas, And Hemangiomata

  • Macrocephaly Pseudopapilledema And Multiple Hemangiomas

  • Ruvalcaba -Myhre-Smith Syndrome

  • Ruvalcaba-Myhre Syndrome

  • Cowden Disease

  • Macrocephaly Pseudopapilledema And Multiple Hemangiomata

  • Cerebellar Granule Cell Hypertrophy And Megalencephaly

  • Cpd6

  • Lhermitte-Duclos Syndrome

  • Pten Hamartoma Tumor Syndromes

  • Cowden Syndrome, Type 1
Pancreatic Cancer

  • Pancreatic Carcinoma

  • Familial Pancreatic Carcinoma

  • Pancreatic Neoplasm

  • Carcinoma Of Pancreas

  • Pancreatic Carcinoma, Familial

  • Malignant Neoplasm Of Pancreas

  • Pancreatic Acinar Carcinoma

  • Pancreatic Tumor

  • Familial Pancreatic Cancer

  • Neoplasm Of The Pancreas

  • Pancreatic Carcinoma, Somatic

  • Pancreatic Cancer, Somatic

  • Ca Body Of Pancreas

  • Ca Head Of Pancreas

  • Ca Tail Of Pancreas

  • Malignant Neoplasm Of Body Of Pancreas

  • Malignant Neoplasm Of Head Of Pancreas

  • Malignant Neoplasm Of Tail Of Pancreas

  • Pancreas Neoplasm

  • Exocrine Cancer

  • Exocrine Pancreas Carcinoma

  • Hereditary Pancreatic Cancer

  • Hereditary Pancreatic Carcinoma

  • PNCA

  • Cancer Of The Pancreas

  • Pancreatic Cancer, Susceptibility To

  • Carcinoma Of Head Of Pancreas

  • Pancreatic Neoplasms

  • Pancreatic Tumors

  • Cancer, Pancreatic

  • Cancer Of Pancreas

  • Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Lymphangioleiomyomatosis

  • Lymphangiomyomatosis

  • LAM

  • Lung Lymphangioleiomyomatosis

  • Pulmonary Lymphangioleiomyomatosis

  • Lymphangioleiomyomatosis, Somatic

  • Lymphangio-Myomatosis
Glioblastoma

  • Glioblastoma Multiforme

  • Gbm

  • Adult Glioblastoma Multiforme

  • Grade Iv Adult Astrocytic Tumor

  • Primary Glioblastoma Multiforme

  • Spongioblastoma Multiforme

  • Adult Glioblastoma

  • Primary Glioblastoma
Diamond-Blackfan Anemia 20

  • DBA20

  • Rps15a-Related Diamond-Blackfan Anemia
Fragile X Syndrome

  • FXS

  • Martin-Bell Syndrome

  • Fraxa Syndrome

  • Marker X Syndrome

  • X-Linked Mental Retardation And Macroorchidism

  • Fragile X Mental Retardation Syndrome

  • Fra Syndrome

  • Mental Retardation, X-Linked, Associated With Marxq28

  • Frax Syndrome

  • Symptomatic Form Of Fragile X Syndrome In Female Carriers

  • Fragile-X Syndrome

  • Fraxe Syndrome
Autism Spectrum Disorder

  • Asd

  • Autism Spectrum Disorders

  • Autistic Continuum

  • Pervasive Developmental Disorder

  • Pervasive Development Disorder

  • Autistic Behavior

  • Autistic Disorder

  • Autistic

  • Autistic Disorder Of Childhood Onset

  • Infantile Autism

  • Childhood Autism

  • Kanner Syndrome

  • Pervasive Developmental Delay Nos

  • Pervasive Developmental Disorder, Not Otherwise Specified
Tuberous Sclerosis

  • Tuberous Sclerosis Syndrome

  • Bourneville'S Disease

  • Epiloia

  • Cerebral Sclerosis

  • Tuberose Sclerosis

  • Tuberous Sclerosis 1

  • Bourneville Disease

  • Bourneville Phakomatosis

  • Pringle'S Disease
Subependymal Giant Cell Astrocytoma

  • Sega

  • Astrocytoma Subependymal Giant Cell

  • Subependymal Giant-Cell Astrocytoma
Subependymal Glioma

  • Mixed Subependymoma-Ependymoma

  • Subependymal Astrocytoma

  • Who Grade I Ependymal Tumor

  • Glioma, Subependymal
Autism

  • Autistic Disorder

  • Autism Susceptibility 1

  • Childhood Autism

  • Autistic Disorder Of Childhood Onset

  • Infantile Autism

  • Kanner'S Syndrome

  • Autistic
Rhabdomyosarcoma
Kidney Benign Neoplasm

  • Renal And Ureteral Tumor

  • Benign Kidney Neoplasm
Pancreatic Adenocarcinoma

  • Adenocarcinoma Of Pancreas

  • Adenocarcinoma Of The Pancreas

  • Pancreas Adenocarcinoma

  • Malignant Exocrine Neoplasm

  • Primary Pancreatic Adenocarcinoma

  • Adenocarcinoma Of Islet Cell Of Pancreas

  • Islet Cell Adenocarcinoma Of Unspecified Site

  • Mixed Adenocarcinoma Islet Cell With Exocrine Of Unspecified Site
Neuroblastoma

  • Nb

  • Neuroblastoma, Susceptibility To

  • Neuroblastomas

  • Central Neuroblastoma
Endometrial Cancer

  • Endometrial Carcinoma

  • Endometrial Neoplasm

  • Malignant Neoplasm Of Endometrium

  • Endometrioid Carcinoma

  • Endometrial Neoplasms

  • Carcinoma, Endometrioid

  • Endometrial Cancer, Familial

  • Endometrial Carcinoma, Somatic

  • Endometrial Cancer, Susceptibility To

  • Endometrial Ca

  • Malignant Endometrial Neoplasm

  • Neoplasm Of Endometrium

  • Primary Malignant Neoplasm Of Endometrium

  • Tumor Of Endometrium

  • Carcinoma Of The Endometrium

  • Endometrioid Carcinoma Of Female Reproductive System

  • ENDMC

  • Carcinoma Endometrioid

  • Endometrial Cancers

  • Cancer, Endometrial

  • Uterine Corpus Cancer
Leukemia, Acute Myeloid

  • Acute Myeloid Leukemia

  • Leukemia, Acute Myelogenous

  • Acute Myelogenous Leukemia

  • AML

  • Leukemia, Acute Myeloid, Susceptibility To

  • Acute Myeloblastic Leukemia

  • Leukemia, Acute Myeloid, Reduced Survival In, Somatic

  • Acute Myeloid Leukaemia

  • Leukemia, Myelocytic, Acute

  • Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome

  • Secondary Aml

  • Acute Myelocytic Leukemia

  • Leukemia, Myeloid, Acute

  • Acute Myeloid Leukemia, Somatic

  • Leukemia, Acute Myeloid, Somatic

  • Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic

  • Acute Myeloblastic Leukaemia

  • Acute Myelogenous Leukaemia

  • Aml - Acute Myeloid Leukemia

  • Acute Myeloid Leukemia With Cebpa Somatic Mutations

  • Aml With Cebpa Somatic Mutations

  • Inherited Acute Myeloid Leukemia

  • Familial Aml

  • Inherited Aml

  • Pure Familial Aml

  • Pure Familial Acute Myeloid Leukemia

  • Secondary Acute Myeloid Leukemia

  • Therapy-Related Aml And Myelodysplastic Syndrome

  • Acute Myeloid Leukemia, Secondary

  • Acute Non-Lymphoblastic Leukemia

  • Acute Non-Lymphocytic Leukemia

  • Acute Biphenotypic Leukemia

  • Acute Undifferentiated Leukemia

  • Acute Myeloblastic Leukaemia With Multilineage Dysplasia

  • Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission

  • Acute Myeloid Leukaemia With Myelodysplasia-Related Features
Colorectal Cancer

  • Colon Cancer

  • Colorectal Carcinoma

  • Colon Carcinoma

  • Colorectal Cancer, Susceptibility To

  • Carcinoma Of Colon

  • CRC

  • Colorectal Cancer With Chromosomal Instability, Somatic

  • Colon Cancer, Somatic

  • Colon Cancer, Susceptibility To

  • Colonic Neoplasms

  • Colorectal Neoplasms

  • Colorectal Cancer, Somatic

  • Colon Cancer, Advanced, Somatic

  • Colonic Carcinoma

  • Colorectal Carcinomas

  • Colon Cancers

  • Colorectal Cancers

  • Cancer, Colorectal, Somatic

  • Cancer, Colon

  • Cancer, Colorectal, Susceptibility To

  • Colorectal Neoplasm

  • Colonic Neoplasm

  • Malignant Tumor Of Colon
Combined Oxidative Phosphorylation Deficiency 33

  • COXPD33
Body Mass Index Quantitative Trait Locus 11

  • OBESITY

  • Obesity, Susceptibility To

  • Leanness, Inherited

  • Obesity, Susceptibility To, Bmiq11

  • Obesity, Mild, Early-Onset

  • Obesity, Association With

  • Obesity, Early-Onset, Susceptibility To

  • Obesity, Severe

  • Obesity, Severe, And Type Ii Diabetes

  • Obesity, Late-Onset

  • BMIQ11

  • Obesity Bmiq11

  • Obesity, Early-Onset

  • Obesity , Susceptibility To

  • Simple Obesity Nos

  • Excess Fat

  • Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified

  • Adiposis
Progressive Myoclonus Epilepsy 8

  • Emp8

  • Pme Type 8

  • Progressive Myoclonic Epilepsy Due To Cers1 Deficiency

  • Progressive Myoclonus Epilepsy Type 8
Lung Cancer

  • Lung Carcinoma

  • Non-Small Cell Lung Carcinoma

  • Lung Cancer, Protection Against

  • Lung Cancer, Susceptibility To

  • Adenocarcinoma Of Lung, Somatic

  • Nonsmall Cell Lung Cancer

  • Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

  • Lung Neoplasm

  • Carcinoma Of Lung

  • Lung Non-Small Cell Carcinoma

  • Non-Small Cell Lung Cancer

  • Nsclc

  • Lung Neoplasms

  • Malignant Neoplasm Of Lung

  • Alveolar Cell Carcinoma

  • Nonsmall Cell Lung Cancer, Somatic

  • Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer, Susceptibility To

  • Lung Cancer, Somatic

  • Lung Cancer, Resistance To

  • Cancer Of Lung

  • Cancer Of Bronchus

  • Cancer Of The Lung

  • Lung Malignancies

  • Lung Malignant Tumors

  • Malignant Lung Tumor

  • Malignant Tumor Of Lung

  • Pulmonary Cancer

  • Pulmonary Carcinoma

  • Pulmonary Neoplasms

  • Respiratory Carcinoma

  • LNCR

  • Adenocarcinoma Of Lung

  • Neoplasm Of Lung

  • Cancer Lung

  • Carcinoma Non-Small Cell Lung

  • Carcinoma, Non-Small-Cell Lung

  • Lung Cancers

  • Lung Carcinomas

  • Cancer, Lung

  • Cancer, Lung, Non-Small Cell

  • Primary Malignant Neoplasm Of Lung

  • Bronchioloalveolar Adenocarcinoma
Breast Cancer

  • Breast Carcinoma

  • Breast Cancer, Familial

  • Malignant Neoplasm Of Breast

  • Male Breast Cancer

  • Breast Cancer, Susceptibility To

  • Breast Cancer, Early-Onset

  • Malignant Tumor Of Breast

  • Carcinoma Of Male Breast

  • Breast Cancer, Invasive Ductal

  • Breast Cancer, Protection Against

  • Breast Cancer, Somatic

  • Breast Cancer, Male

  • Breast Cancer, Lobular, Somatic

  • Breast Tumor

  • Mammary Cancer

  • Mammary Tumor

  • Malignant Neoplasm Of Male Breast

  • Mammary Carcinoma

  • Male Breast Carcinoma

  • Familial Cancer Of Breast

  • Invasive Ductal Breast Carcinoma

  • Breast Cancer Susceptibility

  • Breast Cancer, Male, Susceptibility To

  • Breast Cancer, Early-Onset, Susceptibility To

  • Malignant Tumor Of The Breast

  • Mammary Neoplasm

  • Primary Breast Cancer

  • Neoplasm Of Male Breast

  • Carcinoma Of Breast

  • Breast Cancer In Men

  • Familial Breast Cancer

  • Cancer Of Breast

  • BC

  • Breast Cancer Familial

  • Breast Cancer Familial Male

  • Breast Cancer, Familial Male

  • Breast Male Carcinoma

  • Breast Neoplasms

  • Breast Neoplasms, Male

  • Mammary Tumors

  • Mammary Carcinomas

  • Cancer, Breast

  • Cancer, Breast, Susceptibility

  • Invasive Breast Ductal Carcinoma

  • Breast Neoplasm

  • Susceptibility To Breast Cancer

  • Mammary Neoplasms

  • Animal Mammary Neoplasms

  • Primary Malignant Neoplasm Of Breast

  • Infiltrating Ductal Carcinoma Of Breast

  • Infiltrating Duct Carcinoma Of Unspecified Site

  • Infiltrating Ductular Carcinoma Of Unspecified Site

  • Invasive Breast Carcinoma Of No Special Type

  • Microinvasive Carcinoma Of Breast

  • Carcinoma With Apocrine Differentiation
Cowden Syndrome

  • Cowden Disease

  • Multiple Hamartoma Syndrome

  • Cowden'S Disease

  • Lhermitte-Duclos Disease

  • Cd

  • Cs

  • Mham

  • Dysplastic Gangliocytoma Of Cerebellum

  • Cowden'S Syndrome

  • Hamartoma Syndrome, Multiple
Nervous System Disease

  • Abnormality Of The Nervous System

  • Nervous System Diseases

  • Nervous System Disorder
Benign Ependymoma

  • Ependymoma

  • Epithelial Ependymoma

  • Who Grade Ii Ependymal Tumor

  • Myxopapillary Ependymoma
Prostate Cancer

  • Prostate Carcinoma

  • Prostate Cancer, Familial

  • Prostate Neoplasm

  • Prostate Cancer, Somatic

  • Prostate Cancer, Susceptibility To

  • Prostatic Cancer

  • Prostatic Neoplasms

  • Hereditary Prostate Cancer

  • Prostatic Neoplasm

  • Cancer Of Prostate

  • Carcinoma Of Prostate

  • Familial Prostate Cancer

  • Familial Prostate Carcinoma

  • Malignant Tumor Of Prostate

  • Malignant Neoplasm Of Prostate

  • Prostate Cancer, Familial, Susceptibility To

  • Malignant Tumor Of The Prostate

  • Ngp - New Growth Of Prostate

  • Tumor Of The Prostate

  • Prostate Cancer, Hereditary

  • Cancer Of The Prostate

  • Malignant Neoplasm Of The Prostate

  • Prostatic Carcinoma

  • PC

  • Prca

  • Cancer, Prostate

  • Malignant Prostatic Tumour

  • Malignant Tumour Of Prostate

  • Primary Prostate Cancer

  • Primary Malignant Neoplasm Of Prostate

  • Prostate Gland Cancer
Ovarian Cancer

  • Ovarian Carcinoma

  • Ovarian Neoplasm

  • Malignant Tumour Of Ovary

  • Epithelial Ovarian Cancer

  • Neoplasm Of Ovary

  • Ovarian Neoplasms

  • Ovarian Cancers

  • Malignant Neoplasm Of Ovary

  • Primary Malignant Neoplasm Of Ovary

  • Ovarian Cancer, Somatic

  • Malignant Ovarian Tumor

  • Ovary Neoplasm

  • Primary Ovarian Cancer

  • Tumor Of The Ovary

  • Cancer Of The Ovary

  • Malignant Neoplasm Of The Ovary

  • Malignant Tumor Of The Ovary

  • Ovarian Malignant Tumor

  • OC

  • Ovarian Carcinomas

  • Cancer, Ovarian

  • Cancer Of Ovary

  • Ovary Cancer

  • Ca Ovary
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-148062 RSS0680 Degrader 99.85% Unkown
HY-RS12262 RPS6KB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12263 Rps6kb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12264 Rps6kb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus RPS6KB1 RGD RGD:620683
Mus musculus RPS6KB1 MGD MGI:1270849
Felis catus RPS6KB1 VGNC VGNC:82502
Bos taurus RPS6KB1 VGNC VGNC:34146
Macaca mulatta RPS6KB1 VGNC VGNC:76933
Canis familiaris RPS6KB1 VGNC VGNC:45744
Others RPS6KB1 NCBI