2. Gene
  3. UBE2V2 - ubiquitin conjugating enzyme E2 V2 Gene

UBE2V2 - ubiquitin conjugating enzyme E2 V2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as MMS2; UEV2; EDPF1; UEV-2; DDVIT1; EDAF-1; EDPF-1; DDVit-1

Gene ID: 7336 | Gene type: protein coding

About UBE2V2

Cytogenetic location: 8q11.21 Genomic coordinates (GRCh38): 8:47,997,437-48,064,708 (from NCBI)

This gene has 8 transcripts (splice variants), 194 orthologues and 24 paralogues. Ubiquitous expression in brain (RPKM 22.2), adrenal (RPKM 12.6) and 25 other tissues.

Summary

Ubiquitin-conjugating Enzyme E2 variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene also shares homology with ubiquitin-conjugating Enzyme E2 variant 1 and yeast MMS2 gene product. It may be involved in the differentiation of monocytes and enterocytes. [provided by RefSeq, Jul 2008]

UBE2V2 Products(1)

mRNA Protein Name
NM_003350.3 NP_003341.1 ubiquitin-conjugating enzyme E2 variant 2

UBE2V2 Protein Structure

UQ_con

UQ_con: Ubiquitin-conjugating enzyme (34 - 131)

  • 0
  • 100
  • 145 a.a.
Protein Preferred Names Protein Names

ubiquitin-conjugating enzyme E2 variant 2

1 alpha,25-dihydroxyvitamin D3-inducible

Recombinant UBE2V2 Proteins

Cat. No. Product Name Accession Purity
HY-P71411 UBE2V2 Protein, Human (His) Q15819 (M1-N145) ≥95%

Related Diseases

Diseases Alias
Xeroderma Pigmentosum, Variant Type

Xeroderma Pigmentosum

XPV

Xeroderma Pigmentosum Variant Type

Xeroderma Pigmentosum With Normal Dna Repair Rates

Photosensitivity With Defective Dna Synthesis

Xp

De Sanctis-Cacchione Syndrome

Desanctis-Cacchione Syndrome

Xeroderma Pigmentosa

Xerodermic Idiocy

Xeroderma Pigmentosum Variant

Xp - [Xeroderma Pigmentosum]

Atrophoderma Pigmentosum
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15365 UBE2V2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus UBE2V2 RGD RGD:727838
Bos taurus UBE2V2 VGNC VGNC:36597
Macaca mulatta UBE2V2 VGNC VGNC:84133
Mus musculus UBE2V2 MGD MGI:1917870
Canis familiaris UBE2V2 VGNC VGNC:49665
Others UBE2V2 NCBI