XG - Xg glycoprotein (Xg blood group) Gene

Also Known as PBDX

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 7499

About XG

Cytogenetic location: Xp22.33 Genomic coordinates (GRCh38): X:2,752,040-2,816,500 (from NCBI)

This gene has 6 transcripts (splice variants) and 37 orthologues. Biased expression in skin (RPKM 8.7), fat (RPKM 4.1) and 4 other tissues.

Summary

This gene encodes the XG blood group antigen, and is located at the pseudoautosomal boundary on the short (p) arm of chromosome X. The three 5' exons reside in the pseudoautosomal region and the remaining exons within the X-specific end. A truncated copy of this gene is found on the Y chromosome at the pseudoautosomal boundary. It is transcribed, but not expected to make a Y-chromosome specific gene product. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]

XG Products (3)

mRNA Protein Name
NM_001141919.2 NP_001135391.1 glycoprotein Xg isoform 2 precursor
NM_001141920.2 NP_001135392.1 glycoprotein Xg isoform 3 precursor
NM_175569.3 NP_780778.1 glycoprotein Xg isoform 1 precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
7533029 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

XG Protein Structure

CD99L2

CD99L2: CD99 antigen like protein 2 (25 - 176)

  • 0
  • 100
  • 180 a.a.
Protein Preferred Names Protein Names

glycoprotein Xg

  • Xg blood group (pseudoautosomal boundary-divided on the X chromosome)

Recombinant XG Proteins

Cat. No. Product Name Accession Purity
HY-P73538 XG/Xg blood group Protein, Human (HEK293, His) P55808-2 (Q22-K143) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-P0069 D-JNKI-1 Inhibitor 98.80% Phase 3

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-155666 YXG-158 Degrader / Unkown
HY-RS15872 XG Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca fascicularis XG NCBI NCBI:102136060
Mus musculus XG NCBI
Leporidae XG NCBI
Rattus norvegicus XG NCBI
Macaca mulatta XG NCBI NCBI:705377