Gnaq - G protein subunit alpha q Gene

Also Known as Galphaq

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 81666

Summary

Enables alkylglycerophosphoethanolamine phosphodiesterase activity. Involved in several processes, including activation of Phospholipase C activity; negative regulation of potassium ion transport; and positive regulation of smooth muscle cell proliferation. Located in caveola; cytosol; and synapse. Part of heterotrimeric G-protein complex. Human ortholog(s) of this gene implicated in Sturge-Weber syndrome; congestive heart failure; and familial multiple nevi flammei. Orthologous to human GNAQ (G protein subunit alpha q). [provided by Alliance of Genome Resources, Apr 2022]

Gnaq Products (1)

mRNA Protein Name
NM_031036.3 NP_112298.2 guanine nucleotide-binding protein G(q) subunit alpha

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables alkylglycerophosphoethanolamine phosphodiesterase activity IDA
IDA: Inferred from direct assay
21812758 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
12509430 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
20548297 RGD
Biological Process GO Annotation Evidence Références Source
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
16466740 RGD
involved in negative regulation of potassium ion transport IMP
IMP: Inferred from mutant phenotype
9614229 RGD
involved in phospholipase C-activating G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
9677408 RGD
Cellular Component GO Annotation Evidence Références Source
located in caveola IDA
IDA: Inferred from direct assay
16730745 RGD
part of heterotrimeric G-protein complex IDA
IDA: Inferred from direct assay
21812758 RGD
is active in presynapse IDA
IDA: Inferred from direct assay
17144906 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanine nucleotide-binding protein G(q) subunit alpha

  • guanine nucleotide binding protein (G protein), q polypeptide

  • guanine nucleotide binding protein alpha q subunit

  • guanine nucleotide binding protein, alpha q polypeptide

  • guanine nucleotide regulatory protein G alpha q

  • guanine nucleotide-binding protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS05539 GNAQ Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22188 Gnaq Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28710 Gnaq Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gnaq NCBI NCBI:2776