2. Gene
  3. TRIM56 - tripartite motif containing 56 Gene

TRIM56 - tripartite motif containing 56 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as RNF109

Gene ID: 81844 | Gene type: protein coding

About TRIM56

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:101,085,481-101,097,967 (from NCBI)

This gene has 4 transcripts (splice variants), 119 orthologues and 80 paralogues. Ubiquitous expression in spleen (RPKM 9.3), ovary (RPKM 7.5) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in several processes, including defense response to other organism; positive regulation of macromolecule metabolic process; and protein K63-linked ubiquitination. Predicted to be located in cytoplasm. Predicted to be active in chromatin and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TRIM56 Products(1)

mRNA Protein Name
NM_030961.3 NP_112223.1 E3 ubiquitin-protein ligase TRIM56

TRIM56 Protein Structure

zf-C3HC4

zf-C3HC4: Zinc finger, C3HC4 type (RING finger) (21 - 59)

zf-B_box

zf-B_box: B-box zinc finger (165 - 205)

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  • 600
  • 755 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase TRIM56

RING finger protein 109

Related Diseases

Diseases Alias
Postinfectious Encephalitis

Postinfective Encephalitis

Secondary Encephalitis
Aicardi-Goutieres Syndrome

Aicardi Goutieres Syndrome

Cree Encephalitis

Aicardi-Goutières Syndrome

Encephalopathy With Basal Ganglia Calcification

Ags

Encephalopathy With Intracranial Calcification And Chronic Lymphocytosis Of Cerebrospinal Fluid

Pseudotoxoplasmosis Syndrome

Encephalopathy, Familial Infantile, With Calcification Of Basal Ganglia And Chronic Cerebrospinal Fluid Lymphocytosis

Familial Infantile Encephalopathy With Intracranial Calcification And Chronic Cerebrospinal Fluid Lymphocytosis

Aicardi-Goutieres Syndrome 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15057 TRIM56 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus TRIM56 VGNC VGNC:36342
Felis catus TRIM56 VGNC VGNC:103755
Macaca mulatta TRIM56 VGNC VGNC:79173
Mus musculus TRIM56 MGD MGI:2685298
Rattus norvegicus TRIM56 RGD RGD:40958426