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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
38 Results for "
guanidine-
" in MedChemExpress (MCE) Product Catalog:
Products (38)
38 Results for "guanidine-" in MCE Product Catalog:
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4 Cited Publications
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CHAPS is a cholic acid-derived, sulfobetaine-type zwitterionic detergent and micelle-forming agent. CHAPS exhibits properties of weak cationic or nonionic surfactants in different solution systems, undergoes micellization, and forms small, loose hydrophilic aggregates that are temperature-dependent. CHAPS stabilizes mononucleosomes under different ionic strengths, reduces nucleosome sequence specificity, promotes sliding of histone cores along DNA, solubilizes Tamm-Horsfall protein to reduce its interference with urinary exosome isolation, and maintains vesicle structure and the activity of related proteins at the same time. CHAPS is used to recover native folded fusion proteins, enhance the binding capacity of GST fusion proteins, and restore GST enzyme activity. However, CHAPS cannot refold proteins denatured by urea, guanidine hydrochloride or heat, nor can it construct the structure of intrinsically disordered proteins. CHAPS is commonly used in research on the separation and purification of membrane proteins .
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4 Cited Publications
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3 Cited Publications
Synonyms: Guanidinium chloride; Aminoformamidine hydrochloride
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1 Cited Publications
Synonyms: 2-guanidine-4-methylquinazoline hydrochloride
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GMQ (hydrochloride) is a ASIC (acid-sensing ion) channel activator with an EC50 value of 1.83 mM for ASIC3 at pH 7.4. GMQ (hydrochloride) opens only ASIC3 but no other ASICs at pH 7.4. GMQ (hydrochloride) can be used for neurological disease research .
Cat. No.: HY-121360
CAS No.: 143545-90-8
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Cat. No.: HY-N0930B
CAS No.: 2368870-39-5
Cat. No.: HY-N0930A
CAS No.: 14279-86-8
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Galegine hemisulfate, a guanidine derivative, contributes to weight loss in mice. Galegine hemisulfate activates AMPK in 3T3-L1 adipocytes and L6 myotubes, as well as in the H4IIE rat hepatoma and HEK293 human kidney cell lines. Galegine hemisulfate has antibacterial activity, with minimum inhibitory concentration of 4 mg/L against Staphylococcus aureus strains .
Synonyms: 6M Guanidinium chloride Solution; 6M Aminoformamidine hydrochloride Solution
Cat. No.: HY-W105860S
CAS No.: 2726423-31-8
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Cat. No.: HY-B0178AS
CAS No.: 285977-73-3
Synonyms: Guanidinium-13C,15N3 chloride; Aminoformamidine-13C,15N3 hydrochloride
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GMQ is an acid-sensing ion channel modulator, competitive GABAAR antagonist. GMQ preferentially, potently, competitively inhibits GABAARs. GMQ inhibits α1β2, α1β2γ2, α4β2γ2 and α5β2γ2 GABAARs. GMQ enhances neuronal excitation through inhibition of GABAergic transmission. GMQ has anti-histamine effects in the enteric system, inhibiting gastric acid secretion .
Cat. No.: HY-47228
CAS No.: 113594-64-2
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KB-5492 free base is a potent and selective inhibitor of sigma receptor, inhibits specific [ 3H]1,3-di(2-tolyl)guanidine (DTG) binding to the sigma receptor with an IC50 of 3.15 μM. KB-5492 free base is an anti-ulcer agent .
Cat. No.: HY-W710540
CAS No.: 121616-39-5
Cat. No.: HY-B0178AR
CAS No.: 50-01-1
Synonyms: Guanidinium chloride (Standard); Aminoformamidine hydrochloride (Standard)
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Cat. No.: HY-B0178AS1
CAS No.: 108694-93-5
Synonyms: Guanidinium-d5 chloride; Aminoformamidine-d5 hydrochloride
Cat. No.: HY-W023072S
Synonyms: 1-(4-Aminobutyl)guanidine-d8 dihydrochloride
Cat. No.: HY-105747A
CAS No.: 860385-36-0
Synonyms: N-(3-Phenoxypropyl)guanidine nitrate; (3-Phenoxypropyl)guanidine nitrate
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Guanoxyfen (N-(3-Phenoxypropyl)guanidine) nitrate is a compound that exhibits potent inhibitory activity against the serine protease enzyme TMPRSS2, which plays a crucial role in the infectivity of coronaviruses. Guanoxyfen nitrate is also an effective inhibitor of vasoconstrictor responses to sympathetic nerve stimulation.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
