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  4. 6M Guanidine hydrochloride Solution

6M Guanidine hydrochloride Solution  (Synonyms: 6M Guanidinium chloride Solution; 6M Aminoformamidine hydrochloride Solution)

Cat. No.: HY-B0178B Purity: 98.0%
COA
SDS
Handling Instructions Technical Support

6M Guanidine hydrochloride Solution (6M Guanidinium chloride Solution) is a strong protein denaturant. 6M Guanidine hydrochloride Solution causes proteins to assume a random coil conformation.

For research use only. We do not sell to patients.

6M Guanidine hydrochloride Solution

6M Guanidine hydrochloride Solution Chemical Structure

CAS No. : 50-01-1

Size Price Stock Quantity
Solvent
10 mM * 1 mL in DMSO In-stock
Solvent
50 mL In-stock
Solvent
100 mL In-stock
200 mL   Get quote  
500 mL   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of 6M Guanidine hydrochloride Solution:

6M Guanidine hydrochloride Solution Related Antibodies

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  • Purity & Documentation

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Description

6M Guanidine hydrochloride Solution (6M Guanidinium chloride Solution) is a strong protein denaturant. 6M Guanidine hydrochloride Solution causes proteins to assume a random coil conformation[1].

In Vitro

6M Guanidine hydrochloride Solution induces a random coil conformation in proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

6M Guanidine hydrochloride Solution Related Antibodies
Molecular Weight

95.53

Formula

CH6ClN3
CAS No.
Appearance

Liquid (Density: 1.3 g/cm3)

Color

Colorless to light yellow

SMILES

N=C(N)N.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : ≥ 175 mg/mL (1831.89 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 10.4679 mL 52.3396 mL 104.6792 mL
5 mM 2.0936 mL 10.4679 mL 20.9358 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.0%

SDS (252 KB)

COA (246 KB) HNMR (226 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 10.4679 mL 52.3396 mL 104.6792 mL 261.6979 mL
5 mM 2.0936 mL 10.4679 mL 20.9358 mL 52.3396 mL
10 mM 1.0468 mL 5.2340 mL 10.4679 mL 26.1698 mL
15 mM 0.6979 mL 3.4893 mL 6.9786 mL 17.4465 mL
20 mM 0.5234 mL 2.6170 mL 5.2340 mL 13.0849 mL
25 mM 0.4187 mL 2.0936 mL 4.1872 mL 10.4679 mL
30 mM 0.3489 mL 1.7447 mL 3.4893 mL 8.7233 mL
40 mM 0.2617 mL 1.3085 mL 2.6170 mL 6.5424 mL
50 mM 0.2094 mL 1.0468 mL 2.0936 mL 5.2340 mL
60 mM 0.1745 mL 0.8723 mL 1.7447 mL 4.3616 mL
80 mM 0.1308 mL 0.6542 mL 1.3085 mL 3.2712 mL
100 mM 0.1047 mL 0.5234 mL 1.0468 mL 2.6170 mL
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6M Guanidine hydrochloride Solution Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6M Guanidine hydrochloride Solution50-01-16M Guanidinium chloride Solution 6M Aminoformamidine hydrochloride SolutionBiochemical Assay Reagentsbovine pancreatic ribonucleasedisulfide groupscircular dichroic spectrumcircular dichroic bandprotein denaturantN,N'-diacetyl-L-cystine bismethylamideInhibitorinhibitorinhibit

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