6M Guanidine hydrochloride Solution
Based on 1 Customer Validation
6M Guanidine hydrochloride Solution (6M Guanidinium chloride Solution) is a strong protein denaturant. 6M Guanidine hydrochloride Solution causes proteins to assume a random coil conformation.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 50-01-1
- Formula: CH6ClN3
- Molecular Weight:95.53
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Storage:
Solution, -20°C, 2 years
Biological Activity
6M Guanidine hydrochloride Solution induces a random coil conformation in proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 50-01-1
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Appearance Liquid
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Molecular Weight 95.53
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Formula CH6ClN3
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Color Colorless to light yellow
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SMILES
N=C(N)N.Cl
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Synonyms
6M Guanidinium chloride Solution; 6M Aminoformamidine hydrochloride Solution
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Solvent & Solubility
DMSO : ≥ 175 mg/mL (1831.89 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 10.4679 mL | 52.3396 mL | 104.6792 mL | 261.6979 mL |
| 5 mM | 2.0936 mL | 10.4679 mL | 20.9358 mL | 52.3396 mL | |
| 10 mM | 1.0468 mL | 5.2340 mL | 10.4679 mL | 26.1698 mL | |
| 15 mM | 0.6979 mL | 3.4893 mL | 6.9786 mL | 17.4465 mL | |
| 20 mM | 0.5234 mL | 2.6170 mL | 5.2340 mL | 13.0849 mL | |
| 25 mM | 0.4187 mL | 2.0936 mL | 4.1872 mL | 10.4679 mL | |
| 30 mM | 0.3489 mL | 1.7447 mL | 3.4893 mL | 8.7233 mL | |
| 40 mM | 0.2617 mL | 1.3085 mL | 2.6170 mL | 6.5424 mL | |
| 50 mM | 0.2094 mL | 1.0468 mL | 2.0936 mL | 5.2340 mL | |
| 60 mM | 0.1745 mL | 0.8723 mL | 1.7447 mL | 4.3616 mL | |
| 80 mM | 0.1308 mL | 0.6542 mL | 1.3085 mL | 3.2712 mL | |
| 100 mM | 0.1047 mL | 0.5234 mL | 1.0468 mL | 2.6170 mL |
- 6M Guanidine hydrochloride Solution
- 50-01-1
- 6M Guanidinium chloride Solution
- 6M Aminoformamidine hydrochloride Solution
- Biochemical Assay Reagents
- bovine pancreatic ribonuclease
- disulfide groups
- circular dichroic spectrum
- circular dichroic band
- protein denaturant
- N,N'-diacetyl-L-cystine bismethylamide
- Inhibitor
- inhibitor
- inhibit