2. GPCR/G Protein Immunology/Inflammation
  3. CCR
  4. IDOR-1117-2520

IDOR-1117-2520 is a potent and selective antagonist of CCR6. IDOR-1117-2520 antagonizes the CCL20-mediated calcium flow (IC50 = 63 nM) and inhibits β-arrestin recruitment to human CCR6 (IC50 = 30 nM) in cells expressing recombinant human CCR6. IDOR-1117-2520 can be used for research of autoimmune diseases.

For research use only. We do not sell to patients.

IDOR-1117-2520 Chemical Structure

IDOR-1117-2520 Chemical Structure

CAS No. : 2737274-49-4

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IDOR-1117-2520 Related Antibodies

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Description

IDOR-1117-2520 is a potent and selective antagonist of CCR6. IDOR-1117-2520 antagonizes the CCL20-mediated calcium flow (IC50 = 63 nM) and inhibits β-arrestin recruitment to human CCR6 (IC50 = 30 nM) in cells expressing recombinant human CCR6. IDOR-1117-2520 can be used for research of autoimmune diseases[1].

Molecular Weight

436.55

Formula

C25H32N4O3
CAS No.
Unlabeled CAS

SMILES

CC(C1=CC=C([C@@](C2=CC(C3=NOC(C(C)(O)C)=N3)=CN=C2)(O)C4(CN(C4)C)C)C=C1)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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IDOR-1117-2520 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IDOR-1117-25202737274-49-4CCRCC chemokine receptorlung inflammationautoimmune diseaseInhibitorinhibitorinhibit

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