Bencianol
Bencianol is a the semisynthetic flavinoid, with anti-spasmogenic activities.
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- CAS 番号: 85443-48-7
- 分子式: C28H22O6
- 分子量:454.47
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
Bencianol causes a dose-related (1-100 μg/mL) reversal of contractions induced by 5-hydroxytryptamine, nor-adrenaline, angiotensin II, prostaglandin F2a, and U-46619 (a thromboxane-A2 mimetic). Bencianol is more effective against contractions induced by EC50 compared to maximal concentrations of each agent, and is least effective against the thromboxane-A2 mimetic, U-46619[1]. Bencianol (0.1-100 nM) produces cytoprotective effects against CCl4 induced cell injury on the above three parameters[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 85443-48-7
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分子量 454.47
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分子式 C28H22O6
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SMILES
O[C@@H]1[C@@H](C2=CC=C(OC(C3=CC=CC=C3)(C4=CC=CC=C4)O5)C5=C2)OC6=CC(O)=CC(O)=C6C1
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別名
ZY15051
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Whalley ET, et al. Anti-spasmogenic effects of bencianol (ZY15051) on human cerebral arteries in vitro. Cephalalgia. 1985 Dec;5(4):217-21. [Content Brief]
[2]. Maignan MF, et al. Cytoprotective effects of Bencianol on porcine vascular endothelial cells in vitro. J Submicrosc Cytol. 1986 Jan;18(1):47-51. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)