Brenipatide
Based on 1 Customer Validation
Brenipatide (LY-3537031) is a dual glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) receptor agonist. Brenipatide can be used for the study of metabolic disorders, obesity and diabetes.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.29%
- CAS 番号: 2408921-49-1
- 分子式: C228H354N46O72
- 分子量:4891.52
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保管条件:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
生物活性
製品説明
臨床実験
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 2408921-49-1
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性状 Solid
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分子量 4891.52
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分子式 C228H354N46O72
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Color White to light yellow
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別名
LY-3537031
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配列
{d-Tyr}-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{Leu(aMe)}-Leu-Asp-Lys-{Lys(AEEA-AEEA-γGlu-C20 diacid)}-Ala-Gln-{Aib}-Glu-Phe-Ile-Glu-{Tyr(aMe)}-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
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シーケンスの短縮
{d-Tyr}-{Aib}-EGTFTSDYSI-{Leu(aMe)}-LDK-{K(AEEA-AEEA-γGlu-C20 diacid)}-AQ-{Aib}-EFIE-{Tyr(aMe)}-LIAGGPSSGAPPPS-NH2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (20.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.2044 mL | 1.0222 mL | 2.0444 mL | 5.1109 mL |
| 5 mM | 0.0409 mL | 0.2044 mL | 0.4089 mL | 1.0222 mL | |
| 10 mM | 0.0204 mL | 0.1022 mL | 0.2044 mL | 0.5111 mL | |
| 15 mM | 0.0136 mL | 0.0681 mL | 0.1363 mL | 0.3407 mL | |
| 20 mM | 0.0102 mL | 0.0511 mL | 0.1022 mL | 0.2555 mL |