S1QEL1.1
Based on 1 Customer Validation
S1QEL1.1 is a small molecule inhibitor that specifically inhibits the generation of superoxide and hydrogen peroxide at the IQ site during reverse electron transfer in mitochondrial respiratory chain complex I (Complex I), with an IC50 of 0.07 μM. S1QEL1.1 can significantly reduce the activation of cysteine-aspartic protease (caspase) triggered by endoplasmic reticulum stress. S1QEL1.1 helps to decrease excessive proliferation of stem cells by inhibiting the Reactive Oxygen Species signaling pathway initiated by endoplasmic reticulum stress.
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- 純度: 99.9%
- CAS 番号: 897613-29-5
- 分子式: C23H24N4O3S
- 分子量:436.53
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Apoptosis Compound Library
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Immunology/Inflammation Compound Library
HY-L007
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Metabolism/Protease Compound Library
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NF-κB Signaling Compound Library
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Anti-Aging Compound Library
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Endoplasmic Reticulum Stress Compound Library
HY-L054
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Protease Inhibitor Library
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Highly Selective Inhibitors Library
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MCE Bioactive Compound Library
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High-Throughput Bioactive Compound Library
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Lactylation Compound Library
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Caspase アイソフォーム固有の製品をすべて表示
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生物活性
化学情報
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CAS 番号 897613-29-5
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性状 Solid
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分子量 436.53
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分子式 C23H24N4O3S
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Color White to off-white
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SMILES
O=C(NC1=CC=CC(NC(C)=O)=C1)C(NCCC2=C(C)N=C(C3=CC=C(C)C=C3)S2)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 12.5 mg/mL (28.63 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
DMF : 3 mg/mL (6.87 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (596 KB)
- English - EN (596 KB)
- Français - FR (596 KB)
- Deutsch - DE (596 KB)
- Norwegian - NO (596 KB)
- Español - ES (596 KB)
- Swedish - SV (596 KB)
- Italian - IT (596 KB)
- Korean - KR (596 KB)
- Portuguese - PT (596 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMF / DMSO | 1 mM | 2.2908 mL | 11.4540 mL | 22.9079 mL | 57.2698 mL |
| 5 mM | 0.4582 mL | 2.2908 mL | 4.5816 mL | 11.4540 mL | |
| DMSO | 10 mM | 0.2291 mL | 1.1454 mL | 2.2908 mL | 5.7270 mL |
| 15 mM | 0.1527 mL | 0.7636 mL | 1.5272 mL | 3.8180 mL | |
| 20 mM | 0.1145 mL | 0.5727 mL | 1.1454 mL | 2.8635 mL | |
| 25 mM | 0.0916 mL | 0.4582 mL | 0.9163 mL | 2.2908 mL |
S1QEL1.1 関連分類
HY-129115 関連分類
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