PARP1-IN-57
PARP1-IN-57 is a selective PARP1 inhibitor, with an IC50 of 5 nM against PARP1. PARP1-IN-57 can be used in cancer-related research.
For research use only. We do not sell to patients.
- CAS No.: 3081722-98-4
- Formula: C25H24F2N4O4
- Molecular Weight:482.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PARP-1 5 nM (IC50) |
PARP1-IN-57 (compound 3) exhibits significant inhibitory activity against recombinant PARP1 enzyme (IC50 = 8 nM), while it shows only extremely weak inhibitory activity against recombinant PARP2 enzyme (IC50 > 100 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3081722-98-4
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Molecular Weight 482.48
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Formula C25H24F2N4O4
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SMILES
O=C(NC1CC1)C(N=C2F)=CC=C2OC([C@H]3C)CN3CC4=CC=C(C(OCC5)=C5C(N6)=O)C6=C4F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PARP1-IN-57 Related Classifications
HY-184597 Related Classifications
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