Antibacterial agent 182
Antibacterial agent 182 (compound 8c) is an antibacterial agent that shows antibacterial activity against various Gram-positive bacteria, particularly against Vancomycin-resistant Enterococcus faecalis (MIC ≤0.125 μg/mL). Antibacterial agent 182 inhibits biofilm formation of Staphylococcus aureus and Pseudomonas aeruginosa at sub-MIC doses.
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- 화학식: C14H5Br4F3N2OS
- 분자량:625.88
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NCI-H1299 | IC50 |
8.25 μg/mL
Compound: 8c
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Cytotoxicity against human NCI-H1299 cells measured after 72 hrs by SRB assay
Cytotoxicity against human NCI-H1299 cells measured after 72 hrs by SRB assay
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[PMID: 38382392] |
| NCI-H1975 | IC50 |
4.4 μg/mL
Compound: 8c
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Cytotoxicity against human NCI-H1975 cells measured after 72 hrs by SRB assay
Cytotoxicity against human NCI-H1975 cells measured after 72 hrs by SRB assay
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[PMID: 38382392] |
Chemical Information
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분자량 625.88
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화학식 C14H5Br4F3N2OS
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SMILES
BrC(N1)=C(Br)C(Br)=C1C2=NC(C3=C(O)C(Br)=CC(C(F)(F)F)=C3)=CS2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antibacterial agent 182 Related Classifications
HY-161263 Related Classifications
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