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Cat. No.: HY-187005

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HDAC8 ligand 2

HDAC8 ligand 2 is a HDAC8 ligand that can be used for the synthesis of PROTACs, such as SZUH280 (HY-152147).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₁₆H₁₄N₂O₃
분자량:282.29

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

HDAC8 ligand 2 Chemical Structure

사이즈

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수량

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* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

HDAC8 ligand 2 is a HDAC8 ligand that can be used for the synthesis of PROTACs, such as SZUH280 (HY-152147)^[1].

IC₅₀ & Target^[1]

HDAC8

All HDAC Isoforms :

Chemical Information

분자량 282.29
화학식 C₁₆H₁₄N₂O₃
SMILES

O=C(NO)C1=CC=C2C(N(CC3=CC=C(O)C=C3)C=C2)=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Huang J, et al. Structure-Based Discovery of Selective Histone Deacetylase 8 Degraders with Potent Anticancer Activity. J Med Chem. 2022 Dec 14. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

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HDAC8 ligand 2

All HDAC Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

HDAC8 ligand 2 Related Classifications

HY-187005 Related Classifications