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Cat. No.: HY-19546A

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(R)-BAY-598

(R)-BAY-598 ((R)-4) is a potent inhibitor of protein-lysine methyltransferase SMYD2, with the IC₅₀ of 1.7 μM.

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CAS No.: 1906920-28-2
화학식: C₂₂H₂₀Cl₂F₂N₆O₃
분자량:525.34

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

(R)-BAY-598 Chemical Structure

CAS No.: 1906920-28-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

(R)-BAY-598 ((R)-4) is a potent inhibitor of protein-lysine methyltransferase SMYD2, with the IC₅₀ of 1.7 μM^[1].

All Histone Methyltransferase Isoforms :

Chemical Information

CAS No. 1906920-28-2
분자량 525.34
화학식 C₂₂H₂₀Cl₂F₂N₆O₃
SMILES

O=C(N([C@H]1C(C2=CC=C(Cl)C(Cl)=C2)=NN(/C(NC#N)=N\C3=CC=CC(OC(F)F)=C3)C1)CC)CO
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Discovery and Characterization of a Highly Potent and Selective Aminopyrazoline-Based in Vivo Probe (BAY-598) for the Protein Lysine Methyltransferase SMYD2. J Med Chem. 2016 May 26;59(10):4578-600. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
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(R)-BAY-598

High-Throughput Bioactive Compound Library

All Histone Methyltransferase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

(R)-BAY-598 Related Classifications

HY-19546A Related Classifications