Lamprey LH-RH I
Lamprey LH-RH I is a gonadotropin-releasing hormone, elevates plasma steroid levels and stimulates ovulation in the lamprey without biological activity in other animal models.
For research use only. We do not sell to patients.
- CAS No.: 102634-23-1
- Formula: C58H79N15O15
- Molecular Weight:1226.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Lamprey LH-RH I has a primary mechanism of transport to the pituitary is simple diffusion from neuronal terminals in the neurohypophysis to the adenohypophysis. An additional route is via secretion into the third ventricle and transport by tanycytes to the adenohypophysis[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Female sea-run sea lampreys[1]
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Dosage:5 μg/kg, 50 μg/kg, 100 μg/kg, 200 μg/kg; dissolved in 0.6% NaCl in distilled water
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Administration:Intraperitoneal injection; single dose or twice; observed for 30 days
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Result:Significantly increased estradiol in a dose-related manner.
Resulted 80% of the lampreys ovulation at 200 or 100 μg/kg compared in a doserelated manner.
Chemical Information
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CAS No. 102634-23-1
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Molecular Weight 1226.34
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Formula C58H79N15O15
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Sequence Shortening
{Glp}-HYSLEWKPG-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Sower SA, et al. Comparative biological properties of lamprey gonadotropin-releasing hormone in vertebrates. Endocrinology. 1987 Feb;120(2):773-9. [Content Brief]
[2]. King JC, et al. Neuronal systems immunoreactive with antiserum to lamprey gonadotropin-releasing hormone in the brain of Petromyzon marinus. Cell Tissue Res. 1988 Jul;253(1):1-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lamprey LH-RH I Related Classifications
HY-P3673 Related Classifications
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