(rel)-Lovastatin hydroxy acid-d3 sodium
(rel)-Lovastatin hydroxy acid-d3 ((rel)-Mevinolinic acid-d3) sodium is the deuterium labeled (rel)-Lovastatin hydroxy acid sodium.
For research use only. We do not sell to patients.
- CAS No.: 1217528-38-5
- Formula: C24H34D3NaO6
- Molecular Weight:447.56
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1217528-38-5
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Appearance Solid
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Molecular Weight 447.56
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Formula C24H34D3NaO6
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Color White to off-white
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SMILES
O=C(O[C@H]1C[C@H](C=C2C=C[C@@H]([C@@H]([C@]21[H])CC[C@H](C[C@H](CC(O[Na])=O)O)O)C)C)C(CC)C([2H])([2H])[2H]
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Synonyms
(rel)-Mevinolinic acid-d3 sodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (280 KB)
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SDS (458 KB)
- English - EN (458 KB)
- Français - FR (458 KB)
- Deutsch - DE (458 KB)
- Norwegian - NO (458 KB)
- Español - ES (458 KB)
- Swedish - SV (458 KB)
- Italian - IT (458 KB)
- Korean - KR (458 KB)
- Portuguese - PT (458 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. A W Alberts, eta al. Mevinolin: A Highly Potent Competitive Inhibitor of Hydroxymethylglutaryl-Coenzyme A Reductase and a Cholesterol-Lowering Agent. Proc Natl Acad Sci U S A. 1980 Jul;77(7):3957-61. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(rel)-Lovastatin hydroxy acid-d3 sodium Related Classifications
HY-123672S Related Classifications
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