(rel)-Lovastatin hydroxy acid-d3 sodium
(rel)-Lovastatin hydroxy acid-d3 ((rel)-Mevinolinic acid-d3) sodium is the deuterium labeled (rel)-Lovastatin hydroxy acid sodium.
For research use only. We do not sell to patients.
- CAS No.: 1217528-38-5
- Formula: C24H34D3NaO6
- Molecular Weight:448.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1217528-38-5
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Molecular Weight 448.56
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Formula C24H34D3NaO6
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SMILES
O=C(O[Na])C[C@H](O)C[C@H](O)CC[C@@H]1[C@@]2([H])[C@H](C[C@H](C=C2C=C[C@@H]1C)C)OC(C(C([2H])([2H])[2H])CC)=O
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Synonyms
(rel)-Mevinolinic acid-d3 sodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. A W Alberts, eta al. Mevinolin: A Highly Potent Competitive Inhibitor of Hydroxymethylglutaryl-Coenzyme A Reductase and a Cholesterol-Lowering Agent. Proc Natl Acad Sci U S A. 1980 Jul;77(7):3957-61. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(rel)-Lovastatin hydroxy acid-d3 sodium Related Classifications
HY-123672S Related Classifications
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