MC-(β-Ala)-PABC-(β-D-GlcUA)-amide-PEG1-CH2-CC-885
Based on 1 Customer Validation
MC-(β-Ala)-PABC-(β-D-GlcUA)-amide-PEG1-CH2-CC-885 (Compound Ie) is a neodegrader conjugate, can be used in the synthesis of antibody neoDegrader conjugate (AnDC).
For research use only. We do not sell to patients.
- Purity : 99.37%
- CAS No.: 2722697-86-9
- Formula: C53H61ClN8O18
- Molecular Weight:1133.55
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
Description
In Vitro
MC-(β-Ala)-PABC-(β-D-GlcUA)-amide-PEG1-CH2-CC-885 is a neodegrader conjugate, can be used in the synthesis of antibody neoDegrader conjugate (AnDC)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2722697-86-9
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Appearance Solid
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Molecular Weight 1133.55
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Formula C53H61ClN8O18
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Color White to off-white
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SMILES
O=C1C2=CC=C(CNC(NC3=CC(Cl)=C(C=C3)CCOCCN(C)C(OCC4=CC(NC(CCNC(CCCCCN5C(C=CC5=O)=O)=O)=O)=C(C=C4)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)C(O)=O)=O)=O)C=C2CN1C7C(NC(CC7)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (88.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8822 mL | 4.4109 mL | 8.8218 mL | 22.0546 mL |
| 5 mM | 0.1764 mL | 0.8822 mL | 1.7644 mL | 4.4109 mL | |
| 10 mM | 0.0882 mL | 0.4411 mL | 0.8822 mL | 2.2055 mL | |
| 15 mM | 0.0588 mL | 0.2941 mL | 0.5881 mL | 1.4703 mL | |
| 20 mM | 0.0441 mL | 0.2205 mL | 0.4411 mL | 1.1027 mL | |
| 25 mM | 0.0353 mL | 0.1764 mL | 0.3529 mL | 0.8822 mL | |
| 30 mM | 0.0294 mL | 0.1470 mL | 0.2941 mL | 0.7352 mL | |
| 40 mM | 0.0221 mL | 0.1103 mL | 0.2205 mL | 0.5514 mL | |
| 50 mM | 0.0176 mL | 0.0882 mL | 0.1764 mL | 0.4411 mL | |
| 60 mM | 0.0147 mL | 0.0735 mL | 0.1470 mL | 0.3676 mL | |
| 80 mM | 0.0110 mL | 0.0551 mL | 0.1103 mL | 0.2757 mL |