2. Academic Validation
  3. Progress in the studies on rutaecarpine

Progress in the studies on rutaecarpine

  • Molecules. 2008 Feb 6;13(2):272-300. doi: 10.3390/molecules13020272.
Seung Ho Lee 1,  Jong-Keun Son,  Byeong Seon Jeong,  Tae-Cheon Jeong,  Hyeon Wook Chang,  Eung-Seok Lee,  Yurngdong Jahng
Affiliations

Affiliation

  • 1 College of Pharmacy, Yeungnam University, Gyeongsan 712-749 Korea.
PMID: 18305418 DOI: 10.3390/molecules13020272
Abstract

Rutaecarpine is an indolopyridoquinazolinone alkaloid isolated from Evodia rutaecarpa and related herbs, which has shown a variety of intriguing biological properties such as anti-thrombotic, Anticancer, anti-inflammatory and analgesic, anti-obesity and thermoregulatory, vasorelaxing activity, as well as effects on the cardiovascular and endocrine systems. Recent progress in the studies on the isolation, synthesis, structure-activity relationship studies, biological activities and metabolism of rutaecarpine are reviewed.

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