Chemical Constituents of Vigna luteola and Their Anti-inflammatory Bioactivity

  • Molecules. 2019 Apr 8;24(7):1371. doi: 10.3390/molecules24071371.
Sio-Hong Lam  1 ,  Yue-Chiun Li  2 ,  Ping-Chung Kuo  3 ,  Tsong-Long Hwang  4  5  6 ,  Mei-Lin Yang  7 ,  Chien-Chiao Wang  8 ,  Jason T C Tzen  9
Affiliations
  • 1. School of Pharmacy, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan. [email protected].
  • 2. Graduate Institute of Biotechnology, National Chung-Hsing University, Taichung 402, Taiwan. [email protected].
  • 3. School of Pharmacy, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan. [email protected].
  • 4. Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan. [email protected].
  • 5. Research Center for Industry of Human Ecology, Research Center for Chinese Herbal Medicine, and Graduate Institute of Health Industry Technology, Chang Gung University of Science and Technology, Taoyuan 333, Taiwan. [email protected].
  • 6. Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan. [email protected].
  • 7. School of Pharmacy, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan. [email protected].
  • 8. Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan. [email protected].
  • 9. Graduate Institute of Biotechnology, National Chung-Hsing University, Taichung 402, Taiwan. [email protected].
PMID: 30965630 DOI: 10.3390/molecules24071371
Abstract

Seventy-three compounds were identified from the methanol extract of V. luteola, and among these, three new (1⁻3) were characterized by spectroscopic and mass spectrometric analyses. The isolated constituents were assessed for anti-inflammatory potential evaluation, and several purified principles exhibited significant superoxide anion and Elastase inhibitory effects.

Keywords
elastase release; fabaceae; sesquiterpenoid; superoxide anion generation.
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