Novel Indoline Derivatives Serotonergic Psychedelic Agents as 5‑HT2A Agonists for Treating Psychosis, Mental Illness and CNS Disorders

  • ACS Med Chem Lett. 2026 Apr 27;17(5):1033-1034. doi: 10.1021/acsmedchemlett.6c00208.
Ram W Sabnis  1 ,  Anika R Sabnis  2
Affiliations
  • 1. Arclin USA LLC, 1150 Sanctuary Parkway, Suite 100, Alpharetta, Georgia 30009, United States.
  • 2. Department of Neurologic Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, United States.
PMID: 42157830 DOI: 10.1021/acsmedchemlett.6c00208
Abstract

Provided herein are novel indoline derivatives serotonergic psychedelic agents as 5-HT2A agonists, pharmaceutical compositions, use of such compounds in treating psychosis, mental illness and central nervous system (CNS) disorders and processes for preparing such compounds.

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