ADH4 Protein, Saccharomyces cerevisiae
The ADH4 protein is a specific alcohol dehydrogenase that primarily functions as a mitochondrial formaldehyde dehydrogenase with a unique ethanol preference. It does not affect ethanol production and exhibits reduced activity on primary alcohols with four or more carbon atoms. ADH4 Protein, Saccharomyces cerevisiae is the recombinant ADH4 protein, expressed by E. coli , with tag free.
- Species: Others
- Source: E. coli
-
Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Technical Parameters
-
Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
The ADH4 protein is a specific alcohol dehydrogenase that primarily functions as a mitochondrial formaldehyde dehydrogenase with a unique ethanol preference. It does not affect ethanol production and exhibits reduced activity on primary alcohols with four or more carbon atoms. ADH4 Protein, Saccharomyces cerevisiae is the recombinant ADH4 protein, expressed by E. coli , with tag free.
Background
ADH4 Protein functions as a specific alcohol dehydrogenase with a distinct preference for ethanol, primarily serving as a mitochondrial formaldehyde dehydrogenase without influencing ethanol production. Its enzymatic activity is notably diminished towards primary alcohols containing four carbon atoms or more, with isomers of aliphatic alcohol, secondary alcohols, and glycerol exhibiting no reactivity. While the precise role of ADH4 in yeast metabolism remains unclear, it is established that ADH4 does not play a role in ethanol production during growth on glucose, nor is it involved in the oxidation of ethanol to acetaldehyde. This delineation of substrate specificity and functional characteristics provides insights into ADH4's specific role within cellular processes, shedding light on its unique contribution to alcohol metabolism and mitochondrial formaldehyde oxidation.
Technical Parameters
-
Species Others
-
Source E. coli
-
Tag Tag Free
-
Accession
P10127 (S2-Y382)
-
Gene ID852636
-
Molecular Construction
-
N-term
-
ADH4 (S2-Y382)
Accession # P10127 -
C-term
-
-
Protein Length
Full Length
-
Synonyms
ADH4; Epididymis Secretory Protein Li 4; Alcohol Dehydrogenase 4 (Class II), Pi Polypeptide; Alcohol Dehydrogenase 4; ADH-2; Aldehyde Reductase; All-Trans-Retinol Dehydrogenase [NAD(+)] ADH4; HEL-S-4; Alcohol Dehydrogenase Class II Pi Chain; ADH2; Alcohol
-
AA Sequence
SSVTGFYIPPISFFGEGALEETADYIKNKDYKKALIVTDPGIAAIGLSGRVQKMLEERDLNVAIYDKTQPNPNIANVTAGLKVLKEQNSEIVVSIGGGSAHDNAKAIALLATNGGEIGDYEGVNQSKKAALPLFAINTTAGTASEMTRFTIISNEEKKIKMAIIDNNVTPAVAVNDPSTMFGLPPALTAATGLDALTHCIEAYVSTASNPITDACALKGIDLINESLVAAYKDGKDKKARTDMCYAEYLAGMAFNNASLGYVHALAHQLGGFYHLPHGVCNAVLLPHVQEANMQCPKAKKRLGEIALHFGASQEDPEETIKALHVLNRTMNIPRNLKELGVKTEDFEILAEHAMHDACHLTNPVQFTKEQVVAIIKKAYEY
-
Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz
