2. Recombinant Proteins
  3. CD Antigens Receptor Proteins
  4. Epithelial cell CD Proteins Endothelial cell CD Proteins
  5. TAPA-1/CD81
  6. CD81 Protein, Rat (HEK293)

CD81 Protein, Rat (HEK293)

Cat. No.: HY-P75379
Handling Instructions

CD81, a versatile protein, participates in complement-opsonized particle ingestion, inhibits osteoclast formation, and regulates compartmentalized enzymatic activities. In T cells, CD81 controls intracellular dNTP levels by localizing and degrading SAMHD1. Moreover, it influences cell adhesion and motility, notably in macrophages. CD81 Protein, Rat (HEK293) is the recombinant rat-derived CD81 protein, expressed by HEK293 , with tag free. The total length of CD81 Protein, Rat (HEK293) is 86 a.a., with molecular weight of ~9.7 kDa.

For research use only. We do not sell to patients.

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Description

CD81, a versatile protein, participates in complement-opsonized particle ingestion, inhibits osteoclast formation, and regulates compartmentalized enzymatic activities. In T cells, CD81 controls intracellular dNTP levels by localizing and degrading SAMHD1. Moreover, it influences cell adhesion and motility, notably in macrophages. CD81 Protein, Rat (HEK293) is the recombinant rat-derived CD81 protein, expressed by HEK293 , with tag free. The total length of CD81 Protein, Rat (HEK293) is 86 a.a., with molecular weight of ~9.7 kDa.
Background

CD81 is a protein involved in various cellular processes. It plays a role in complement-opsonized particle ingestion, prevents the formation of osteoclasts responsible for bone resorption, and regulates enzymatic activities within cellular compartments. In T cells, CD81 helps control intracellular dNTP levels by localizing and degrading the protein SAMHD1. It is also involved in cell adhesion and motility, particularly in macrophages.
Species

Rat
Source

HEK293
Tag

Tag Free
Accession

Q62745 (K116-K201)
Gene ID

25621  [NCBI]
Molecular Construction
N-term
CD81 (K116-K201)
Accession # Q62745
C-term
Synonyms
CD81 antigen; CD81; CVID6; TAPA-1; TSPAN28
Molecular Weight

Approximately 9.7 kDa
Purity

Greater than 85% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

CD81 Protein, Rat (HEK293) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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