CDCP1 Protein, Rhesus (HEK293, His)

The CDCP1 protein has been implicated in cell adhesion and matrix association, suggesting a role in important cellular interactions. Its phosphorylation suggests a dynamic function in regulating anchorage, migration, proliferation, or differentiation. CDCP1 Protein, Rhesus (HEK293, His) is the recombinant Rhesus Macaque-derived CDCP1 protein, expressed by HEK293 , with C-His labeled tag. The total length of CDCP1 Protein, Rhesus (HEK293, His) is 639 a.a., with molecular weight of 80-115 kDa.

CDCP1 Protein appears to be involved in cell adhesion and cell matrix association, suggesting a role in mediating interactions crucial for cellular processes. Its potential involvement in the regulation of anchorage versus migration or proliferation versus differentiation, as indicated by its phosphorylation, implies a dynamic role in modulating cell behavior. Additionally, CDCP1 may serve as a novel marker for leukemia diagnosis and immature hematopoietic stem cell subsets, providing potential diagnostic and therapeutic insights. As a member of the tetraspanin web implicated in tumor progression and metastasis, CDCP1 interacts with key molecules including CDH2/N-cadherin, CDH3/P-cadherin, SDC1/syndecan-1, SDC4/syndecan-4, the serine protease ST14/MT-SP1, SRC, and PRKCG/protein kinase C gamma. The diversity of its interactions underscores its potential impact on cellular processes and suggests a multifaceted role in both normal and pathological conditions. Further exploration of CDCP1's functions and regulatory mechanisms could provide deeper insights into its contributions to cellular dynamics and its potential as a therapeutic target.

Immobilized Rhesus CDCP1 at 2 μg/mL(100 μl/Well) on the plate. Dose response curve for Anti-CDCP1 Antibody, hFc Tag with the EC₅₀ of ≤17.5 ng/mL determined by ELISA.

Rhesus Macaque

HEK293

C-His

XP_001114659 (A29-T667)

714333  [NCBI]

80-115 kDa

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized powder.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 5% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.