CKMT2 Protein, Rat (His, Solution)

CKMT2 Protein, predicted to have ubiquitin-protein transferase activity, is involved in regulating the epidermal growth factor receptor signaling pathway. It engages in autoubiquitination and ubiquitin-dependent protein catabolic processes via the multivesicular body sorting pathway. Positioned in the cytosol, CKMT2 demonstrates ubiquitous expression across tissues, emphasizing its involvement in diverse cellular processes and physiological functions throughout the body, with notable levels in the heart, fat, and 25 other tissues. CKMT2 Protein, Rat (His, Solution) is the recombinant rat-derived CKMT2 protein, expressed by E. coli , with N-His labeled tag. The total length of CKMT2 Protein, Rat (His, Solution) is 380 a.a., with molecular weight of ~47.0 kDa.

CKMT2 Protein is predicted to possess ubiquitin-protein transferase activity and is implicated in negative regulation of the epidermal growth factor receptor signaling pathway, protein autoubiquitination, and ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. The protein is anticipated to be located in the cytosol. Notably, CKMT2 exhibits ubiquitous expression across various tissues, with notable levels observed in the heart, fat, and 25 other tissues, suggesting its involvement in diverse cellular processes and physiological functions throughout the body.

Rat

E. coli

N-His

NP_001121124.1（D40-K419）

688698

DAREQHKLFPPSADYPDLRKHNNCMAECLTPTIYAKLRNKMTPSGYTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHPTDLDASKITHGQFDERYVLSSRVRTGRSIRGLSLPPACSRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQDIKVPPPLPQFGRK

Approximately 47.0 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

Solution

Supplied as a 0.2 μm filtered solution of 50 mM Hepes, 750 mM NaCl, pH 6.0.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.