CLEC10A/CD301 Protein, Mouse (HEK293, His)
Based on 1 Customer Validation
The CLEC10A/CD301 protein is a receptor that recognizes terminal galactose and N-acetylgalactosamine units and is involved in a variety of biological processes.It may play a crucial role by promoting interactions between tumor-killing macrophages and tumor cells.CLEC10A/CD301 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CLEC10A/CD301 protein, expressed by HEK293 , with C-His labeled tag.
- Species: Mouse
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
The CLEC10A/CD301 protein is a receptor that recognizes terminal galactose and N-acetylgalactosamine units and is involved in a variety of biological processes.It may play a crucial role by promoting interactions between tumor-killing macrophages and tumor cells.CLEC10A/CD301 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CLEC10A/CD301 protein, expressed by HEK293 , with C-His labeled tag.
Background
CLEC10A/CD301 Protein is a receptor that specifically recognizes terminal galactose and N-acetylgalactosamine units, suggesting its involvement in various biological processes. It may play a crucial role in facilitating the interaction between tumoricidal macrophages and tumor cells. Additionally, CLEC10A/CD301 Protein has been implicated in the recruitment of inflammatory monocytes to adipose tissue during diet-induced obesity. It forms homooligomers and interacts with SIGLEC1, potentially acting as a counter-receptor for CLEC10A/CD301 Protein in lymph nodes.
Technical Parameters
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Species Mouse
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Source HEK293
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Tag C-8*His
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Accession
P49300 (Q57-S304)
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Molecular Construction
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N-term
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CLEC10A (Q57-S304)
Accession # P49300 -
8*His
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C-term
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Protein Length
Extracellular Domain
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Synonyms
CLEC10A; DC-Asialoglycoprotein Receptor; Prev. CLECSF13; MGL; Prev. CLECSF14; C-Type (Calcium Dependent, Carbohydrate-Recognition Domain) Lectin, Superfamily Member 13 (Macrophage-Derived); HML; CDNA FLJ78539, Highly Similar To Homo Sapiens C-Type Lectin
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AA Sequence
QNSQLRRDLGTLRATLDNTTSKIKAEFQSLDSRADSFEKGISSLKVDVEDHRQELQAGRDLSQKVTSLESTVEKREQALKTDLSDLTDHVQQLRKDLKALTCQLANLKNNGSEVACCPLHWTEHEGSCYWFSESEKSWPEADKYCRLENSHLVVVNSLEEQNFLQNRLANVVSWIGLTDQNGPWRWVDGTDFEKGFKNWAPLQPDNWFGHGLGGGEDCAHITTGGPWNDDVCQRTFRWICEMKLAKES
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Predicted Molecular Mass
29.4 kDa
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Molecular Weight
Approximately 38-45 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Glycosylation
Yes
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Purity
≥ 95%, as determined by Bis-Tris PAGE.
Product Properties
Lyophilized powder.
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4, 8% trehalose.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
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Data Sheet (236 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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