DPY30 Protein, Human (His)
DPY30 Protein, Human (His) is the recombinant human-derived DPY30, expressed by E. coli , with N-6*His labeled tag.
- Species: Human
- Source: E. coli
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
DPY30 Protein, Human (His) is the recombinant human-derived DPY30, expressed by E. coli , with N-6*His labeled tag.
Background
DPY30 is a component of the MLL1/MLL complex, involved in the methylation of histone H3 at Lys-4, particularly trimethylation. Histone H3 Lys-4 methylation serves as a specific tag for epigenetic transcriptional activation. It may play a role in histone H3 acetylation. In teratocarcinoma cells, DPY30 is critical for retinoic acid-induced neural lineage differentiation by regulating gene induction and H3 Lys-4 methylation at key developmental loci. It may also have a direct or indirect role in endosomal transport. by similar: Other MLL complex members may share analogous functions.
Technical Parameters
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Species Human
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Source E. coli
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Tag N-6*His
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Accession
Q9C005 (E2-N99)
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Gene ID84661
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Molecular Construction
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N-term
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6*His
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DPY30 (E2-N99)
Accession # Q9C005 -
C-term
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Protein Length
Full Length
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Synonyms
DPY30; Protein Dpy-30 Homolog; Dpy-30 Histone Methyltransferase Complex Regulatory Subunit; Dpy-30-Like Protein; HDPY-30; Dpy-30L; Saf19; Dpy-30 Homolog (C. Elegans); Cps25; Dpy-30 Homolog
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AA Sequence
EPEQMLEGQTQVAENPHSEYGLTDNVERIVENEKINAEKSSKQKVDLQSLPTRAYLDQTVVPILLQGLAVLAKERPPNPIEFLASYLLKNKAQFEDRN
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Predicted Molecular Mass
12 kDa
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Molecular Weight
Approximately 15-20 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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