GNAZ Protein, Human (His-SUMO)

GNAZ proteins are members of G proteins that are crucial in regulating or transducing signals in a variety of transmembrane signaling systems. G proteins have three units, α, β, and γ, and play a key role in signal transmission across cell membranes. GNAZ Protein, Human (His-SUMO) is the recombinant human-derived GNAZ protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of GNAZ Protein, Human (His-SUMO) is 354 a.a., with molecular weight of ~56.8 kDa.

GNAZ, a member of guanine nucleotide-binding proteins (G proteins), functions as a critical modulator or transducer in diverse transmembrane signaling systems. Comprising three units—alpha, beta, and gamma—G proteins play a pivotal role in transmitting signals across cell membranes. The alpha chain of GNAZ harbors the guanine nucleotide binding site, essential for its regulatory activities. Additionally, GNAZ interacts with ADGRB2, suggesting its involvement in specific signaling pathways and cellular processes.

Human

E. coli

N-6*His;N-SUMO

P19086 (G2-C355)

2781  [NCBI]

GCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALRIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFSRSSEYHLEDNAAYYLNDLERIAAADYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLTICFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC

Approximately 56.8 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.