2. 組換えタンパク質
  3. Others
  4. GPR52 Protein, Human (HEK293, Flag, His)

GPR52 Protein, Human (HEK293, Flag, His) is the recombinant human-derived GPR52, expressed by HEK293 , with His, Flag labeled tag. ,

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

Surface Plasmon Resonance (SPR) アッセイサ-ビス   Protein Expression Service

>
容量 在庫状況
50 μg   お問い合わせ  
100 μg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

Top Publications Citing Use of Products

  • 生物活性

  • 技術的パラメータ

  • 特性

  • 説明

製品説明

GPR52 Protein, Human (HEK293, Flag, His) is the recombinant human-derived GPR52, expressed by HEK293 , with His, Flag labeled tag. ,
Background

GPR52 is a Gs-coupled receptor activated by the antipsychotic drug reserpine, leading to increased intracellular cAMP and its internalization. It may play a role in locomotor activity by modulating dopamine, NMDA, and ADORA2A-induced locomotor responses, with these behavioral changes accompanied by alterations in dopamine receptor signaling pathways in the striatum. Additionally, GPR52 modulates HTT levels via cAMP-dependent but PKA-independent mechanisms by activating RAB39B, which translocates HTT to the endoplasmic reticulum, thereby preventing proteasomal degradation. by similar: These findings suggest GPR52 as a potential therapeutic target in neuropsychiatric disorders.
Species

Human
Source

HEK293
Tag

His;Flag
Accession

Q9Y2T5 (G17-K235, R262-M340, A130W, A264L, W278Q, C314P, S318A, N321D, V323T)
Gene ID

9293
Protein Length

Partial
Synonyms
G-protein coupled receptor 52; GPR52; Homo sapiens; Human; G-protein coupled receptor; Receptor; Transducer
AA Sequence

RYLMVLFRITSVFYMLQLPYIIYFLLESSRVLDNPTLSFLTTWLAISNSFCNPVIYALSDSTFRLGLRRLSETMCTSCM

Predicted Molecular Mass
65.5 kDa
Glycosylation
Yes
純度

≥ 95%, as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
ドキュメンテーション
取扱説明書 (2659 KB)

GPR52 Protein, Human (HEK293, Flag, His) 関連分類

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • モル濃度計算機

  • 希釈カルキュレーター

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2

最近チェックした製品:

オンラインお問い合わせ

Your information is safe with us. * Required Fields.

製品名

  

カスタマ需要量 *

お名前 *

 

タイトル

PC 用メールアドレス *

 

電話番号 *

デパートメント

 

組纖名 *

市区町村

都道府県

国或いは地域 *

      

必ず会社名を記載ください。個人への返信は行いません。

備考

バルクお問い合わせ

Inquiry Information

製品名:
GPR52 Protein, Human (HEK293, Flag, His)
製品番号:
HY-P703263
数量:
MCE 日本正規代理店:

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

製品名

  

Lot #

お名前 *

 

国或いは地域 *

PC 用メールアドレス *

     

電話番号 *

 

組纖名 *

備考

Request for HNMR Report

We have received your request and will respond to you as soon as possible.