LSR Protein, Human (HEK293, His)
Based on 1 Customer Validation
LSR Protein, Human (HEK293, His) is the recombinant human-derived LSR protein, expressed by HEK293, with C-8*His tag.
- Species: Human
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
LSR Protein, Human (HEK293, His) is the recombinant human-derived LSR protein, expressed by HEK293, with C-8*His tag.
Background
LSR likely plays a role in the clearance of triglyceride-rich lipoproteins from the blood. In the presence of free fatty acids, LSR binds chylomicrons, LDL, and VLDL, facilitating their subsequent cellular uptake (by similarity). Additionally, LSR maintains epithelial barrier function by recruiting MARVELD2/tricellulin to tricellular tight junctions (by similarity).
Technical Parameters
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Species Human
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Source HEK293
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Tag C-8*His
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Accession
Q86X29-1 (P22-D259)
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Gene ID51599
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Molecular Construction
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N-term
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LSR (P22-D259)
Accession # Q86X29-1 -
8*His
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C-term
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Protein Length
Partial Extracellular Domain
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Synonyms
LSR; Lipolysis-Stimulated Lipoprotein Receptor; Lipolysis Stimulated Lipoprotein Receptor; Lipolysis-Stimulated Remnant; ILDR3; Liver-Specific BHLH-Zip Transcription Factor; Angulin-1; LISCH Protein; LISCH7; LSR Protein; Immunoglobulin-Like Domain Contain
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AA Sequence
PSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGLGSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPTQPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQGNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLGRTSGVAELLPGFQAGPIED
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Predicted Molecular Mass
27.4 kDa
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Molecular Weight
Approximately 15-25 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Purity
≥ 95%, as determined by Bis-Tris PAGE.
Product Properties
Lyophilized powder.
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
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Data Sheet (236 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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