LSR Protein, Human (HEK293, His)

LSR Protein, Human (HEK293, His) is the recombinant human-derived LSR protein, expressed by HEK293, with C-8*His tag.

LSR likely plays a role in the clearance of triglyceride-rich lipoproteins from the blood. In the presence of free fatty acids, LSR binds chylomicrons, LDL, and VLDL, facilitating their subsequent cellular uptake (by similarity). Additionally, LSR maintains epithelial barrier function by recruiting MARVELD2/tricellulin to tricellular tight junctions (by similarity).

Human

HEK293

C-8*His

Q86X29-1 (P22-D259)

51599

Partial

PSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGLGSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPTQPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQGNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLGRTSGVAELLPGFQAGPIED

Approximately 15-25 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.

≥ 95%, as determined by Bis-Tris PAGE.

Lyophilized powder.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.