Osteomodulin Protein, Mouse (HEK293, His, solution)

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Osteomodulin protein likely contributes to biomineralization processes, influencing the formation and regulation of mineralized tissues.It binds to osteoblasts via the alpha(V)beta(3)-integrin, indicating involvement in cell adhesion and interactions with the extracellular matrix.The specific binding to the alpha(V)beta(3)-integrin suggests its potential role in mediating cellular processes associated with integrin signaling.Osteomodulin Protein, Mouse (HEK293, His) is the recombinant mouse-derived Osteomodulin protein, expressed by HEK293 , with C-His labeled tag.

For research use only. We do not sell to patients.
  • Species: Mouse
  • Source: HEK293
  • Storage:
    Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
  • Biological Activity
  • Technical Parameters
  • Product Properties
  • Documentation
  • Help & FAQs

Biological Activity

Description

Osteomodulin protein likely contributes to biomineralization processes, influencing the formation and regulation of mineralized tissues.It binds to osteoblasts via the alpha(V)beta(3)-integrin, indicating involvement in cell adhesion and interactions with the extracellular matrix.The specific binding to the alpha(V)beta(3)-integrin suggests its potential role in mediating cellular processes associated with integrin signaling.Osteomodulin Protein, Mouse (HEK293, His) is the recombinant mouse-derived Osteomodulin protein, expressed by HEK293 , with C-His labeled tag.

Background

Osteomodulin protein is thought to play a role in biomineralization processes, potentially contributing to the formation and regulation of mineralized tissues. It functions by binding to osteoblasts through the alpha(V)beta(3)-integrin, indicating its involvement in cell adhesion and interaction with the extracellular matrix. Moreover, osteomodulin specifically binds to the alpha(V)beta(3)-integrin, suggesting its potential significance in mediating cellular processes associated with integrin signaling.

Technical Parameters

  • Species Mouse
  • Source HEK293
  • Tag C-10*His
  • Accession
  • Gene ID
  • Molecular Construction
    • N-term
    • Osteomodulin (Q21-I423)
      Accession # O35103
    • 10*His
    • C-term
  • Protein Length

    Full Length of Mature Protein

  • Synonyms

    OMD; Keratan Sulfate Proteoglycan Osteomodulin; Osteomodulin; Osteoadherin Proteoglycan; SLRR2C; KSPG Osteomodulin; Osteoadherin; OSAD

  • AA Sequence

    QYEAYRWDDDYDQEPNEDYDPEFQFHQNIEYGVPFYNNILGCAKECFCPTNFPTSMYCDNRKLKTIPIIPMHIQQLNLQFNDIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLSNLQQLHLEHNNLEEFPFPLPKSLERLLLGYNEISILPTNAMDGLVNVTMLDLCYNHLSDSMLKEKTLSKMEKLMQLNLCNNRLESMPLGLPSSLMYLSLENNSISSIPDNYFDKLPKLHALRISHNKLEDIPYDIFNLSNLIELNVGHNKLKQAFYIPRNLEHLYLQNNEIESINVTMICPSPDPVHHHHLTYLRVDQNKLKEPISSYIFFCFPRIHSIYYGEQRSTNGETIQLKTQVFRSYQEEEEEDDHDSQDNTLEGQEVSDEHYNSHYYEMQEWQDTI

  • Predicted Molecular Mass

    48.8 kDa

  • Molecular Weight

    Approximately 60-80 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

  • Glycosylation

    Yes

  • Purity

    ≥ 95%, as determined by reducing SDS-PAGE.

Product Properties

Appearance

Solution

Formulation

Supplied as a 0.22 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Storage & Stability

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Calculators

Reconstitution Calculator

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

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=
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Desired Reconstitution Concentration Desired Reconstitution Concentration
Dilution Calculator

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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The Specific Activity Calculator Equation
  • Specific Activity (Unit/mg)
  • Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) Specific Activity (Unit/mg)
Unit/mg
= 106 ÷
Biological Activity (ED50) Biological Activity (ED50)
106 ÷
ng/mL
MOQ
Minimum order quantity
100 mg

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