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Osteomodulin Protein, Mouse (HEK293, His)

Cat. No.: HY-P76530
COA Handling Instructions

Osteomodulin protein likely contributes to biomineralization processes, influencing the formation and regulation of mineralized tissues. It binds to osteoblasts via the alpha(V)beta(3)-integrin, indicating involvement in cell adhesion and interactions with the extracellular matrix. The specific binding to the alpha(V)beta(3)-integrin suggests its potential role in mediating cellular processes associated with integrin signaling. Osteomodulin Protein, Mouse (HEK293, His) is the recombinant mouse-derived Osteomodulin protein, expressed by HEK293 , with C-His labeled tag. The total length of Osteomodulin Protein, Mouse (HEK293, His) is 423 a.a., with molecular weight of 60-70 KDa.

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Description

Osteomodulin protein likely contributes to biomineralization processes, influencing the formation and regulation of mineralized tissues. It binds to osteoblasts via the alpha(V)beta(3)-integrin, indicating involvement in cell adhesion and interactions with the extracellular matrix. The specific binding to the alpha(V)beta(3)-integrin suggests its potential role in mediating cellular processes associated with integrin signaling. Osteomodulin Protein, Mouse (HEK293, His) is the recombinant mouse-derived Osteomodulin protein, expressed by HEK293 , with C-His labeled tag. The total length of Osteomodulin Protein, Mouse (HEK293, His) is 423 a.a., with molecular weight of 60-70 KDa.

Background

Osteomodulin protein is thought to play a role in biomineralization processes, potentially contributing to the formation and regulation of mineralized tissues. It functions by binding to osteoblasts through the alpha(V)beta(3)-integrin, indicating its involvement in cell adhesion and interaction with the extracellular matrix. Moreover, osteomodulin specifically binds to the alpha(V)beta(3)-integrin, suggesting its potential significance in mediating cellular processes associated with integrin signaling.

Species

Mouse

Source

HEK293

Tag

C-His

Accession

O35103 (M1-I423)

Gene ID

27047  [NCBI]

Molecular Construction
N-term
Osteomodulin (M1-I423)
Accession # O35103
His
C-term
Synonyms
Keratan sulfate proteoglycan osteomodulin; OSAD; OMD; SLRR2C
Molecular Weight

60-70 kDa.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Appearance

Solution.

Formulation

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

N/A.

Storage & Stability

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Documentation

Osteomodulin Protein, Mouse (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Osteomodulin Protein, Mouse (HEK293, His)
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HY-P76530
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