PANX1 Protein, Human (HEK293)
PANX1 Protein, Human (HEK293) is the recombinant human-derived PANX1, expressed by HEK293 , with tag Free labeled tag. ,
- Species: Human
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
PANX1 Protein, Human (HEK293) is the recombinant human-derived PANX1, expressed by HEK293 , with tag Free labeled tag. ,
PANX1 is an ion channel involved in various physiological functions, including blood pressure regulation, apoptotic cell clearance, and oogenesis. It forms anion-selective channels with relatively low conductance and an order of permeabilities: nitrate > iodide > chloride >> aspartate = glutamate = gluconate (By similarity). It can release ATP upon activation through phosphorylation or cleavage at the C-terminus. It may also function as a Ca2+-leak channel to regulate ER Ca2+ homeostasis.
Technical Parameters
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Species Human
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Source HEK293
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Tag Tag Free
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Accession
Q96RD7-1 (M1-C426 )
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Gene ID24145
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Protein Length
Full Length of Isoform-1
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Synonyms
PANX1; Innexin; Pannexin 1; Pannexin; MRS1; OZEMA7; UNQ2529; OOMD7; PX1; PANX; Pannexin-1
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AA Sequence
MAIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSARDLDMRDGACSVPGVTENLGQSLWEVSESHFKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKSSGQGIDPMLLLTNLGMIKMDVVDGKTPMSAEMREEQGNQTAELQGMNIDSETKANNGEKNARQRLLDSSC
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Predicted Molecular Mass
48.8 kDa
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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