patZ Protein, E.coli (His, StrepⅡ)
The patZ protein catalyzes the acetylation of lysine residues in a variety of target proteins, including RNase R and RNase II, during exponential phase. patZ Protein, E.coli (His, Strep) is the recombinant E. coli-derived patZ protein, expressed by E. coli , with N-Strep, N-6*His labeled tag.
- Species: E.coli
- Source: E. coli
-
Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Technical Parameters
-
Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
The patZ protein catalyzes the acetylation of lysine residues in a variety of target proteins, including RNase R and RNase II, during exponential phase. patZ Protein, E.coli (His, Strep) is the recombinant E. coli-derived patZ protein, expressed by E. coli , with N-Strep, N-6*His labeled tag.
Background
patZ protein plays a pivotal role in cellular regulation through its acetyl-CoA-dependent acetylation of lysine residues on a diverse array of target proteins. Notably, it catalyzes the acetylation of RNase R and RNase II in exponential phase cells, impacting RNA metabolism. Additionally, patZ is essential for glucose-dependent acetylation on multiple lysines of alpha, beta, and beta' subunits of RNA polymerase (RNAP), influencing transcriptional processes. The acetyltransferase activity of patZ extends to key cellular components, including acetyl-coenzyme A synthetase (Acs) and the chromosomal replication initiator protein DnaA, leading to the inhibition of their functional activities. Furthermore, patZ overexpression results in widespread protein acetylation and hinders cellular motility. These findings underscore the multifaceted role of patZ in orchestrating diverse cellular processes through post-translational modifications.
Technical Parameters
-
Species E.coli
-
Source E. coli
-
Tag N-StrepⅡ;N-6*His
-
Accession
P76594 (S2-S886)
-
Gene ID947056
-
Molecular Construction
-
N-term
-
StrepⅡ-6*His
-
patZ (S2-S886)
Accession # P76594 -
C-term
-
-
Protein Length
Full Length
-
Synonyms
PATZ1; POZ-, AT Hook-, And Zinc Finger-Containing Protein 1; Prev. ZNF278; Zinc Finger And BTB Domain-Containing Protein 19; ZBTB19; Zinc Finger Sarcoma Gene Protein; RIAZ; BTB-POZ Domain Zinc Finger Transcription Factor; PATZ; BTB/POZ Domain Zinc Finger
-
AA Sequence
SQRGLEALLRPKSIAVIGASMKPNRAGYLMMRNLLAGGFNGPVLPVTPAWKAVLGVLAWPDIASLPFTPDLAVLCTNASRNLALLEELGEKGCKTCIILSAPASQHEDLRACALRHNMRLLGPNSLGLLAPWQGLNASFSPVPIKRGKLAFISQSAAVSNTILDWAQQRKMGFSYFIALGDSLDIDVDELLDYLARDSKTSAILLYLEQLSDARRFVSAARSASRNKPILVIKSGRSPAAQRLLNTTAGMDPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGDRLMIISNGAAPAALALDALWSRNGKLATLSEETCQKLRDALPEHVAISNPLDLRDDASSEHYIKTLDILLHSQDFDALMVIHSPSAAAPATESAQVLIEAVKHHPRSKYVSLLTNWCGEHSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLRETPALPSNLTSNTAEAHLLLQQAIAEGATSLDTHEVQPILQAYGMNTLPTWIASDSTEAVHIAEQIGYPVALKLRSPDIPHKSEVQGVMLYLRTANEVQQAANAIFDRVKMAWPQARVHGLLVQSMANRAGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEDQAVVALPPLNMNLARYLVIQGIKSKKIRARSALRPLDVAGLSQLLVQVSNLIVDCPEIQRLDIHPLLASGSEFTALDVTLDISPFEGDNESRLAVRPYPHQLEEWVELKNGERCLFRPILPEDEPQLQQFISRVTKEDLYYRYFSEINEFTHEDLANMTQIDYDREMAFVAVRRIDQTEEILGVTRAISDPDNIDAEFAVLVRSDLKGLGLGRRLMEKLITYTRDHGLQRLNGITMPNNRGMVALARKLGFNVDIQLEEGIVGLTLNLAQREES
-
Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz
