SLC44A1 Protein, Human (HEK293)
The SLC44A1 protein acts as a choline/H+ and high-affinity ethanolamine/H+ antiporter and is critical for regulating cellular choline and ethanolamine transport. Its dual function actively redistributes intracellular ethanolamine and balances the CDP-Cho and CDP-Etn arms of the Kennedy pathway. SLC44A1 Protein, Human (HEK293) is the recombinant human-derived SLC44A1 protein, expressed by HEK293.
- Species: Human
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
The SLC44A1 protein acts as a choline/H+ and high-affinity ethanolamine/H+ antiporter and is critical for regulating cellular choline and ethanolamine transport. Its dual function actively redistributes intracellular ethanolamine and balances the CDP-Cho and CDP-Etn arms of the Kennedy pathway. SLC44A1 Protein, Human (HEK293) is the recombinant human-derived SLC44A1 protein, expressed by HEK293.
SLC44A1 protein functions as a choline/H+ antiporter, playing a pivotal role in the regulation of cellular choline transport as documented in various studies. Additionally, it acts as a high-affinity ethanolamine/H+ antiporter, thereby controlling the supply of extracellular ethanolamine for the CDP-Etn pathway. This dual functionality allows SLC44A1 to actively redistribute intracellular ethanolamine, maintaining a balance between the CDP-Cho and CDP-Etn arms of the Kennedy pathway. The involvement of SLC44A1 in these processes is crucial for membrane synthesis and myelin production, highlighting its significance in fundamental cellular functions and suggesting potential implications for membrane homeostasis and neural development.
Technical Parameters
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Species Human
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Source HEK293
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Tag Tag Free
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Accession
Q8WWI5 (M1-A657)
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Gene ID23446
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Molecular Construction
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N-term
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SLC44A1 (M1-A657)
Accession # Q8WWI5-1 -
C-term
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Protein Length
Full Length
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Synonyms
SLC44A1; Solute Carrier Family 44 (Choline Transporter), Member 1; Prev. CDW92; Choline Transporter-Like Protein; CTL1; CD92 Antigen; CD92; CONATOC; Choline Transporter-Like Protein 1; CDw92; CHTL1; Solute Carrier Family 44 Member 1; CDW92 Antigen
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AA Sequence
MGCCSSASSAAQSSKREWKPLEDRSCTDIPWLLLFILFCIGMGFICGFSIATGAAARLVSGYDSYGNICGQKNTKLEAIPNSGMDHTQRKYVFFLDPCNLDLINRKIKSVALCVAACPRQELKTLSDVQKFAEINGSALCSYNLKPSEYTTSPKSSVLCPKLPVPASAPIPFFHRCAPVNISCYAKFAEALITFVSDNSVLHRLISGVMTSKEIILGLCLLSLVLSMILMVIIRYISRVLVWILTILVILGSLGGTGVLWWLYAKQRRSPKETVTPEQLQIAEDNLRALLIYAISATVFTVILFLIMLVMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTFFALVLFWVYWIMTLLFLGTTGSPVQNEQGFVEFKISGPLQYMWWYHVVGLIWISEFILACQQMTVAGAVVTYYFTRDKRNLPFTPILASVNRLIRYHLGTVAKGSFIITLVKIPRMILMYIHSQLKGKENACARCVLKSCICCLWCLEKCLNYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVATINTVGDFMLFLGKVLIVCSTGLAGIMLLNYQQDYTVWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYNDGSPGREFYMDKVLMEFVENSRKAMKEAGKGGVADSRELKPMASGASSA
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Predicted Molecular Mass
74 kDa
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Molecular Weight
Approximately 56 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 80%, as determined by reducing SDS-PAGE.
Product Properties
Solution
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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