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  4. TAC1 Protein, Human (His)

TAC1 Protein, Human (His)

Cat. No.: HY-P71128
COA Handling Instructions

The TAC1 protein is a member of the tachykinin family that coordinates multiple physiological effects. Under the influence of TAC1, tachykinin excites neurons, induces behavior, acts as a potent vasodilator, secretagogue, and triggers smooth muscle contraction. TAC1 Protein, Human (His) is the recombinant human-derived TAC1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of TAC1 Protein, Human (His) is 110 a.a., with molecular weight of ~15 kDa.

For research use only. We do not sell to patients.

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50 μg $510 In-stock
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  • Biological Activity

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Description

The TAC1 protein is a member of the tachykinin family that coordinates multiple physiological effects. Under the influence of TAC1, tachykinin excites neurons, induces behavior, acts as a potent vasodilator, secretagogue, and triggers smooth muscle contraction. TAC1 Protein, Human (His) is the recombinant human-derived TAC1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of TAC1 Protein, Human (His) is 110 a.a., with molecular weight of ~15 kDa.

Background

The TAC1 protein, a member of the tachykinin family, serves as a key orchestrator of diverse physiological effects. Tachykinins, active peptides under the influence of TAC1, demonstrate the capacity to excite neurons, elicit behavioral responses, function as potent vasodilators and secretagogues, and induce the contraction of numerous smooth muscles, either directly or indirectly. TAC1's regulatory role in these multifaceted processes highlights its significance in modulating neuronal activity, behavior, vascular responses, and smooth muscle function, showcasing its integral role in various physiological pathways.

Species

Human

Source

E. coli

Tag

N-6*His

Accession

P20366 (E20-R129)

Gene ID
Molecular Construction
N-term
6*His
TAC1 (E20-R129)
Accession # P20366
C-term
Synonyms
Protachykinin-1; PPT; TAC1
AA Sequence

EEIGANDDLNYWSDWYDSDQIKEELPEPFEHLLQRIARRPKPQQFFGLMGKRDADSSIEKQVALLKALYGHGQISHKRHKTDSFVGLMGKRALNSVAYERSAMQNYERRR

Molecular Weight

Approximately 15 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Appearance

Solution.

Formulation

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCI, 150 mM NaCl, 10% glycerol, 2 M Urea, 1 mM EDTA, pH 8.0.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Storage & Stability

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Documentation

TAC1 Protein, Human (His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
TAC1 Protein, Human (His)
Cat. No.:
HY-P71128
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