TAC1 Protein, Human (His)
Based on 1 Customer Validation
The TAC1 protein is a member of the tachykinin family that coordinates multiple physiological effects. Under the influence of TAC1, tachykinin excites neurons, induces behavior, acts as a potent vasodilator, secretagogue, and triggers smooth muscle contraction. TAC1 Protein, Human (His) is the recombinant human-derived TAC1 protein, expressed by E. coli , with N-6*His labeled tag.
- Species: Human
- Source: E. coli
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
The TAC1 protein is a member of the tachykinin family that coordinates multiple physiological effects. Under the influence of TAC1, tachykinin excites neurons, induces behavior, acts as a potent vasodilator, secretagogue, and triggers smooth muscle contraction. TAC1 Protein, Human (His) is the recombinant human-derived TAC1 protein, expressed by E. coli , with N-6*His labeled tag.
The TAC1 protein, a member of the tachykinin family, serves as a key orchestrator of diverse physiological effects. Tachykinins, active peptides under the influence of TAC1, demonstrate the capacity to excite neurons, elicit behavioral responses, function as potent vasodilators and secretagogues, and induce the contraction of numerous smooth muscles, either directly or indirectly. TAC1's regulatory role in these multifaceted processes highlights its significance in modulating neuronal activity, behavior, vascular responses, and smooth muscle function, showcasing its integral role in various physiological pathways.
Technical Parameters
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Species Human
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Source E. coli
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Tag N-6*His
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Accession
P20366 (E20-R129)
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Molecular Construction
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N-term
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6*His
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TAC1 (E20-R129)
Accession # P20366 -
C-term
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Protein Length
Full Length of Mature Protein
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Synonyms
TAC1; Neurokinin 1; Prev. NKNA; Neuromedin L; Prev. TAC2; Substance K; NPK; Substance P; Tachykinin, Precursor 1 (Substance K, Substance P, Neurokinin 1, Neurokinin 2, Neuromedin L, Neurokinin Alpha, Neuropeptide K, Neuropeptide Gamma); PPT; Neuropeptide
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AA Sequence
EEIGANDDLNYWSDWYDSDQIKEELPEPFEHLLQRIARRPKPQQFFGLMGKRDADSSIEKQVALLKALYGHGQISHKRHKTDSFVGLMGKRALNSVAYERSAMQNYERRR
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Predicted Molecular Mass
15.2 kDa
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Molecular Weight
Approximately 14-18 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Solution
Supplied as a 0.22 μm filtered solution of 20 mM Tris-HCI, 150 mM NaCl, 10% glycerol, 2 M Urea, 1 mM EDTA, pH 8.0.
Note: For SPR assay, please replace the buffer. Primary amine components (e.g., Tris, imidazole) can affect protein-coupled chips.
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
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Data Sheet (235 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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