2. Anti-infection
  3. SARS-CoV
  4. SARS-CoV-2 Mpro-IN-56

SARS-CoV-2 Mpro-IN-56 is an orally active SARS-CoV-2 Mpro inhibitor with an IC50 of 0.026 μM. SARS-CoV-2 Mpro-IN-56 can be used for the research of COVID-19.

For research use only. We do not sell to patients.

SARS-CoV-2 Mpro-IN-56

SARS-CoV-2 Mpro-IN-56 Chemical Structure

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

SARS-CoV-2 Mpro-IN-56 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

SARS-CoV-2 Mpro-IN-56 is an orally active SARS-CoV-2 Mpro inhibitor with an IC50 of 0.026 μM. SARS-CoV-2 Mpro-IN-56 can be used for the research of COVID-19[1].

In Vitro

SARS-CoV-2 Mpro-IN-56 (Compound 35) has a CC50 of 277 μM in HEK-293 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

SARS-CoV-2 Mpro-IN-56 Related Antibodies
In Vivo

SARS-CoV-2 Mpro-IN-56 (50-1500 mg/kg; oral gavage; single dose) has an LD50 of 947.6 mg/kg BW in female Swiss albino mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Swiss female albino mice (25-30 g)[1]
Dosage: 50, 250, 500, 750, 1000, 1250, 1500 mg/kg BW
Administration: p.o.; single dose
Result: Resulted in 100% mortality (3/3 mice) at 1500 mg/kg BW.
Resulted in 80% mortality (4/5 mice) at 1250 mg/kg BW.
Resulted in 57.14% mortality (4/7 mice) at 1000 mg/kg BW.
Resulted in 22.22% mortality (2/9 mice) at 750 mg/kg BW.
Resulted in 0% mortality (9/9 mice per dose) at 500, 250, and 50 mg/kg BW.
Calculated an oral LD50 of 947.6 mg/kg BW (95% CI: 892.3-1003 mg/kg BW; R2=0.9930).
Determined an oral LD100 of 1500 mg/kg BW.
Molecular Weight

620.69

Formula

C34H22F2N4O2S2
SMILES

O=C(NC1=CC=C(SC(N(C/2=O)C(C3=CC=C(F)C(F)=C3)SC2=C/C4=CNC5=C4C=CC=C5)=N6)C6=C1)/C=C/C7=CC=CC=C7
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

SARS-CoV-2 Mpro-IN-56 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SARS-CoV-2 Mpro-IN-56SARS-CoVSARS coronavirusSARS-CoV-2 MproHEK-293 cellsSwiss female albino miceInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
SARS-CoV-2 Mpro-IN-56
Cat. No.:
HY-182065
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.