SARS-CoV-2 PLpro-IN-6
SARS-CoV-2 PLpro-IN-6 is an irreversible SARS-CoV-2 papain-like protease inhibitor with an IC50 value of 0.059 μM. SARS-CoV-2 PLpro-IN-6 exhibits antiviral activity and can be used in studies related to COVID-19.
For research use only. We do not sell to patients.
- Formula: C36H40F2N6O4
- Molecular Weight:658.74
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
SARS-CoV-2 PLpro-IN-6 (compound 45) (5-60 min) inhibits recombinant SARS-CoV-2 PLPro in a time-dependent manner, with an IC50 of 0.059 μM after 60 min of incubation[1].
SARS-CoV-2 PLpro-IN-6 (48 h) exhibits antiviral activity against SARS-CoV-2 in A549 cells, with an EC50 of 2.1 μM at 48 hpi, and shows no cytotoxicity at concentrations up to 100 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 658.74
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Formula C36H40F2N6O4
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SMILES
CC1=C2OC3(CCC2=CC=C1C4=CC=NC(C)=C4)CCN(CC3)CC5=C(C=CC=N5)CCC(NNC(/C=C/C(N6CC(F)(C6)F)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SARS-CoV-2 PLpro-IN-6 Related Classifications
HY-181641 Related Classifications
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