455 Results for "

O2

" in MedChemExpress (MCE) Product Catalog:
Products (455)

455 Results for "O2" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-161104
CAS No.: 2252448-93-2
Kv2.1-IN-1 is an orally active and blood-brain barrier penetrant Kv2.1 inhibitor with an IC50 of 0.07 μM. Kv2.1-IN-1 exhibits a selectivity >130 fold over other K +, Na +, and Ca 2+ ion channels. Kv2.1-IN-1 decreases the apoptosis of HEK293 cells induced by H2O2. Kv2.1-IN-1 produces significant neuroprotection efficacy in middle cerebral artery occlusion (MCAO) rat. Kv2.1-IN-1 can be used for the study of ischemic stroke .
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Cat. No.: HY-109110
CAS No.: 435327-40-5
Purity:  96.02%
Synonyms: GC-4419; M-40419
Avasopasem manganese (GC4419; M-40419) is a potent superoxide dismutase mimetic that rapidly and specifically converts O2 *- to hydrogen peroxide (H2O2), arresting the initiation of this cascade. Avasopasem manganese can be used for the research of severe oral mucositis (SOM) and cancer .
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Cat. No.: HY-E70014
CAS No.: 37250-84-3
Synonyms: FAD-GDH; Glucose 1-dehydrogenase
Research Areas:  

Others

FAD-dependent glucose dehydrogenase (EC 1.1.5.9), or glucose dehydrogenase (FAD)/Pseudomonas glucose dehydrogenase. FAD-dependent glucose dehydrogenase is insensitive to O2 and displays high substrate specificity to glucose and thus is especially attractive enzymes for use in glucose biosensor applications .
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Cat. No.: HY-40145
CAS No.: 254454-54-1
1-Boc-3-iodoazetidine acts as a bifunctional additive for lithium-oxygen (Li-O2) batteries and can be used to enhance the performance of Li-O2 batteries. 1-Boc-3-iodoazetidine is applied in the synthesis of C3-functionalized azetidines and C2-functionalized azetidines via a lithium/iodine exchange or β-elimination/lithiation reaction sequence [2].
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Cat. No.: HY-W012313
CAS No.: 3736-77-4
Synonyms: 2,2'-Cyclouridine; O2,2'-Cyclouridine
2,2'-Anhydrouridine (2,2'-Cyclouridine) is a nucleoside analog. 2,2'-Anhydrouridine is an important intermediate in the synthesis of other nucleoside-related compounds [2].
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Cat. No.: HY-159854
CAS No.: 2639634-77-6
Target:  

Liposome

Research Areas:  

Cancer

C14-O2 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
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Cat. No.: HY-P1012
CAS No.: 110880-55-2
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease Endocrinology

[Sar9,Met(O2)11]-Substance P is a tachykinin NK1 receptor selective agonist.
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Cat. No.: HY-B1776AS
CAS No.: 1173019-26-5
Spermidine-d8 (hydrochloride)e is the deuterium labeled Spermidine trihydrochloride. Spermidine hydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine hydrochloride significantly decreases the H2O2 and O2.- contents .
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Cat. No.: HY-150175
CAS No.: 1786411-17-3
Target:  

Fluorescent Dye

Research Areas:  

Inflammation/Immunology

HKSOX-1 and its derivatives (HKSOX-1r and HKSOX-1m) are novel fluorescent probes designed for highly sensitive and selective detection of the superoxide anion radical (O2 •−) in cellular environments. These probes utilize an aryl trifluoromethanesulfonate group that undergoes O2 •−-mediated cleavage, releasing a free phenol and emitting fluorescence. They demonstrate excellent specificity and sensitivity across various pH ranges, withstand interference from strong oxidants and reductants typical in cellular contexts. HKSOX-1r, optimized for cellular retention, has been effectively employed in diverse assays including confocal imaging, flow cytometry, and zebrafish embryo studies, highlighting its utility in investigating O2 •− roles in inflammation, mitochondrial stress, and other physiological processes .
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Cat. No.: HY-W013794
CAS No.: 14167-18-1
Synonyms: N,N′-Bis(salicylidene)ethylenediaminocobalt(II)
Target:  

Influenza Virus

Research Areas:  

Infection

Salcomine (N,N’-Bis(salicylidene)ethylenediaminocobalt II) is a carrier of O2 and oxidation catalysts. Salcomine has anti-influenza virus activity .
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Cat. No.: HY-116694
CAS No.: 536-08-3
Digallic acid is an antioxidant, antimutagenic, antigenotoxic, and anti-hyperuricemic compound. Digallic acid is a reverse transcriptase and XOD, URAT1 (IC50: 5.34 μM) inhibitor. Digallic acid scavenges DPPH· and O2·− radicals. Digallic acid induces apoptosis. Digallic acid can be isolated from the fruits of Pistascia lentiscus [2] .
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Cat. No.: HY-D3002
CAS No.: 2981401-58-3
ONOO-/O2- tracker probe is a dual-responsive near-infrared fluorescent probe. ONOO-/O2- tracker probe will only emit a strong fluorescence signal when both peroxynitrite (ONOO⁻) and superoxide anion (O₂•⁻), the two key reactive oxygen/nitrogen species, are present simultaneously. ONOO-/O2- tracker probe can be used as a biomarker detection tool for drug-induced liver injury (DILI) .
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Cat. No.: HY-D1156
CAS No.: 1786411-19-5
HKSOX-1m (5/6-mixture) is a O2 fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O2 over a broad range of pH, strong oxidants, and abundant reductants found in cells .
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Cat. No.: HY-P3782
Target:  

Amyloid-β

Research Areas:  

Others

(Met(O2)35)-Amyloid β-Protein (1-42) is a peptide .
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Cat. No.: HY-P1012A
CAS No.: 2828433-10-7
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease Endocrinology

[Sar9,Met(O2)11]-Substance P TFA is a tachykinin NK1 receptor selective agonist.
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Cat. No.: HY-N7161
CAS No.: 466663-11-6
3-O-(2'E,4'E-Decadienoyl)-ingenol is a natural diterpenoid that shows cytotoxicity against human normal cell lines L-O2 and GES-1, with IC50s of 8.22 μM and 6.67 μM, respectively .
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Cat. No.: HY-117457
CAS No.: 1444382-92-6
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

BPIC is a DNA intercalator agent and also an anti-cancer agent. BPIC scavenge ∙OH, ∙O2(-), and NO free radicals .
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Cat. No.: HY-139701
CAS No.: 2733559-66-3
Target:  

HDAC

Research Areas:  

Cancer

NI-Pano (CH-03) is a novel hypoxia-activated KDAC inhibitor. NI-Pano (CH-03) is reduced in an O2-dependent manner to release panobinostat.
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Cat. No.: HY-125575
CAS No.: 1380411-57-3
Target:  

Carbonic Anhydrase

Research Areas:  

Cancer

FC11409B is an ureido-sulfamate carbonic anhydrase IX (CAIX) inhibitor. FC11409B inhibits proliferation and migration of breast cancer cell lines in both hypoxic (0.5% O2) and normoxic conditions (21% O2). FC11409B also inhibits 3D spheroid of breast cancer subtypes invasion. FC11409B is promising for research of breast and ovarian cancers .
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Cat. No.: HY-P2744
CAS No.: 9027-23-0
Synonyms: Ribulose 1,5-bisphosphate carboxylase
Research Areas:  

Others

Ribulose bisphosphate carboxylase (Ribulose 1,5-bisphosphate carboxylase) catalyses the carboxylation (CO2 addition) or oxygenation (O2 addition) of d-ribulose-1,5-bisphosphate (RuBP) and the subsequent carbon–carbon cleavage to form two molecules of 3-phospho-d-glycerate (PGA) (with CO2) or one molecule of PGA and one molecule of 2-phospho-glycolate (PG; with O2) .
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