1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. BPIC

BPIC is a DNA intercalator agent and also an anti-cancer agent. BPIC scavenge ∙OH, ∙O2(-), and NO free radicals.

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BPIC

BPIC Estructura química

No. CAS : 1444382-92-6

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Descripciòn

BPIC is a DNA intercalator agent and also an anti-cancer agent. BPIC scavenge ∙OH, ∙O2(-), and NO free radicals[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
0.96 μM
Compound: BPIC
Antiproliferative activity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 25648297]
CCRF S-180 IC50
0.96 μM
Compound: BPIC
Antiproliferative activity against mouse S180 cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against mouse S180 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 25648297]
HeLa IC50
0.96 μM
Compound: BPIC
Antiproliferative activity against human HeLa cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 25648297]
HepG2 IC50
0.96 μM
Compound: BPIC
Antiproliferative activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 25648297]
HL-60 IC50
0.96 μM
Compound: BPIC
Antiproliferative activity against human HL60 cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HL60 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 25648297]
HT-29 IC50
0.96 μM
Compound: BPIC
Antiproliferative activity against human HT-29 cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HT-29 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 25648297]
K562 IC50
0.96 μM
Compound: BPIC
Antiproliferative activity against human K562 cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against human K562 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 25648297]
SH-SY5Y IC50
0.96 μM
Compound: BPIC
Antiproliferative activity against human SH-SY5Y cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against human SH-SY5Y cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 25648297]
Peso molecular

452.46

Fòrmula

C27H20N2O5

No. CAS
SMILES

O=C(C1=C(O)C=CC(C2=NC(C(OCC3=CC=CC=C3)=O)=CC4=C2NC5=C4C=CC=C5)=C1)OC

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación
Referencias
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  • Calculadora de molaridad

  • Calculadora de dilución

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
BPIC
Cat. No.:
HY-117457
Cantidad:
MCE Japan Authorized Agent: