country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-117457

Copy Link Print Information

BPIC

BPIC is a DNA intercalator agent and also an anti-cancer agent. BPIC scavenge ∙OH, ∙O2(-), and NO free radicals.

For research use only. We do not sell to patients.

CAS No.: 1444382-92-6
Formula: C₂₇H₂₀N₂O₅
Molecular Weight:452.46

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

BPIC Chemical Structure

CAS No.: 1444382-92-6

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

BPIC is a DNA intercalator agent and also an anti-cancer agent. BPIC scavenge ∙OH, ∙O2(-), and NO free radicals^[1].

All DNA/RNA Synthesis Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human A549 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
CCRF S-180	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against mouse S180 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against mouse S180 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
HeLa	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human HeLa cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
HepG2	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
HL-60	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human HL60 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human HL60 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
HT-29	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human HT-29 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
K562	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human K562 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human K562 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
SH-SY5Y	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human SH-SY5Y cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human SH-SY5Y cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]

Chemical Information

CAS No. 1444382-92-6
Molecular Weight 452.46
Formula C₂₇H₂₀N₂O₅
SMILES

O=C(C1=C(O)C=CC(C2=NC(C(OCC3=CC=CC=C3)=O)=CC4=C2NC5=C4C=CC=C5)=C1)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Shan Li, et al. BPIC: A novel anti-tumor lead capable of inhibiting inflammation and scavenging free radicals. Bioorg Med Chem Lett. 2015 Mar 1;25(5):1146-50. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote

Amount: USD 0.00

Biological Activity
- Description
Chemical Information
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
Purity:
Quantity:

BPIC

All DNA/RNA Synthesis Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

BPIC Related Classifications

HY-117457 Related Classifications