Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
110 Results for "
Ca2 binding
" in MedChemExpress (MCE) Product Catalog:
Products (110)
110 Results for "Ca2 binding" in MCE Product Catalog:
Cat. No.: HY-P71742
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HSPA5; Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa); Prev. GRP78; HSP70 Family Protein 5; BiP; Heat Shock 70kD Protein 5 (Glucose-Regulated Protein, 78kD); Immunoglobulin Heavy Chain-binding Protein; Endoplasmic Reticulum Lumenal Ca(2+)-B
Species:
Mouse
Source:
P. pastoris
Cat. No.: HY-P72239
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HSPA5; Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa); Prev. GRP78; HSP70 Family Protein 5; BiP; Heat Shock 70kD Protein 5 (Glucose-Regulated Protein, 78kD); Immunoglobulin Heavy Chain-binding Protein; Endoplasmic Reticulum Lumenal Ca(2+)-B
Species:
Human
Source:
E. coli
Cat. No.: HY-P790088
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HSPA5; Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa); Prev. GRP78; HSP70 Family Protein 5; BiP; Heat Shock 70kD Protein 5 (Glucose-Regulated Protein, 78kD); Immunoglobulin Heavy Chain-binding Protein; Endoplasmic Reticulum Lumenal Ca(2+)-B
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P704486
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HSPA5; Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa); Prev. GRP78; HSP70 Family Protein 5; BiP; Heat Shock 70kD Protein 5 (Glucose-Regulated Protein, 78kD); Immunoglobulin Heavy Chain-binding Protein; Endoplasmic Reticulum Lumenal Ca(2+)-B
Species:
Human
Source:
P. pastoris
Cat. No.: HY-W041308R
CAS No.: 64359-81-5
Synonyms: Kathon 930 (Standard)
Research Areas:
DCOIT (Standard) (Kathon 930 (Standard)) is the analytical standard of DCOIT (HY-W041308). This product is intended for research and analytical applications. DCOIT (Kathon 930) is an isothiazolinone biocide and environmental pollutant that directly binds to G protein α subunits, with KD values of 0.92 mM and 0.4 mM for Gαs and Gαi, respectively. Binding of DCOIT to Gαi enhances the interaction between Gαi and mitochondrial calcium uniporter (MCU), alters the subcellular distribution of intracellular Ca 2+, and activates PKC/MEK/ERK signaling. DCOIT upregulates CYP19a transcription and aromatase activity, thereby disrupting steroid hormone homeostasis. DCOIT is used in studies of reproductive endocrine disruption and environmental toxicology .
Cat. No.: HY-N0215S16
CAS No.: 136056-01-4
Synonyms: (S)-2-Amino-3-phenylpropionic acid-13C-1
Cat. No.: HY-P705984
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HSPA5; Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa); Prev. GRP78; HSP70 Family Protein 5; BiP; Heat Shock 70kD Protein 5 (Glucose-Regulated Protein, 78kD); Immunoglobulin Heavy Chain-binding Protein; Endoplasmic Reticulum Lumenal Ca(2+)-B
Species:
Others
Source:
HEK293
Cat. No.: HY-P71742Y
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HSPA5; Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa); Prev. GRP78; HSP70 Family Protein 5; BiP; Heat Shock 70kD Protein 5 (Glucose-Regulated Protein, 78kD); Immunoglobulin Heavy Chain-binding Protein; Endoplasmic Reticulum Lumenal Ca(2+)-binding Protein Grp78; Heat Shock Protein 70 Family Protein 5; Epididymis Secretory Sperm binding Protein Li 89n; Heat Shock Protein Family A Member 5; Endoplasmic Reticulum Chaperone BIP; Endoplasmic Reticulum Chaperone BiP; HEL-S-89n; 78 KDa Glucose-Regulated Protein; GRP-78; binding-Immunoglobulin Protein; Heat Shock Protein Family A (Hsp70) Member 5; Glucose-Regulated Protein, 78kDa
Species:
Mouse
Source:
P. pastoris
Cat. No.: HY-P705465
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HSPA5; Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa); Prev. GRP78; HSP70 Family Protein 5; BiP; Heat Shock 70kD Protein 5 (Glucose-Regulated Protein, 78kD); Immunoglobulin Heavy Chain-binding Protein; Endoplasmic Reticulum Lumenal Ca(2+)-binding Protein Grp78; Heat Shock Protein 70 Family Protein 5; Epididymis Secretory Sperm binding Protein Li 89n; Heat Shock Protein Family A Member 5; Endoplasmic Reticulum Chaperone BIP; Endoplasmic Reticulum Chaperone BiP; HEL-S-89n; 78 KDa Glucose-Regulated Protein; GRP-78; binding-Immunoglobulin Protein; Heat Shock Protein Family A (Hsp70) Member 5; Glucose-Regulated Protein, 78kDa
Species:
Human
Source:
E. coli
Cat. No.: HY-108659
CAS No.: 202982-98-7
Research Areas:
NF340 is a P2Y11 receptor inhibitor with a pIC50 of 7.3-7.7 against human P2Y11 receptor, and it exhibits high selectivity over other P2Y family receptors. NF340 binds to the ATP-binding amino acid residues of the P2Y11 receptor to inhibit its activity, block nociceptive activity, and reduce spinal dorsal horn P2Y11 receptor upregulation induced by spinal nerve injury. NF340 attenuates the NFκB signaling pathway activated by IL-1β by decreasing IκBα phosphorylation, nuclear p65 accumulation, and NFκB promoter activity. NF340 inhibits IL-1β-induced pro-inflammatory cytokine expression, reduces intracellular ROS and 4-HNE levels, and suppresses IL-1β-induced matrix metalloproteinase expression in primary fibroblast-like synoviocytes. NF340 inhibits ATP-induced elevation of intracellular Ca 2+ concentration and cell migration in human hepatocellular carcinoma cells. NF340 can be used in the research of neuropathic pain, myocardial ischemia/reperfusion injury, inflammatory pain, rheumatoid arthritis, and hepatocellular carcinoma .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
