2 Results for "

(1R,2R)-Calhex 231

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "(1R,2R)-Calhex 231" in MCE Product Catalog:

17
17 Cited Publications
Cat. No.: HY-17365
CAS No.: 79517-01-4
Synonyms: SMS 201-995 acetate
Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.
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Cat. No.: HY-103320B
Purity:  99.07%
Target:  

CaSR

Research Areas:  

Metabolic Disease

(1R,2R)-Calhex 231 hydrochloride is the isomer of Calhex 231 hydrochloride (HY-103320A), and can be used as an experimental control. Calhex 231 hydrochloride is a CaSR inhibitor via negative allosteric modulation. Calhex 231 hydrochloride blocks Ca 2+-induced accumulation of [ 3H]inositol phosphate with an IC50 of 0.39 μM in HEK293 cells. Calhex 231 hydrochloride has the potential for diabetic cardiomyopathy (DCM) treatment .
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