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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
(2S,3R,4S)-ASX-173
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "(2S,3R,4S)-ASX-173" in MCE Product Catalog:
Cat. No.: HY-175282A
CAS No.: 2748800-07-7
(2S,3R,4S)-ASX-173 is the (2S,3R,4S)-enantiomer of ASX-173 (HY-175282). ASX-173 is an orally active inhibitor of asparagine synthetase (ASNS) (IC50 = 0.113 μM, Ki = 0.4 nM). ASX-173 enhances the anticancer activity of L-asparaginase (ASNase) (HY-P1923). ASX-173 disrupts nucleotide synthesis and induces leukemia cell cycle arrest, apoptosis and autophagy in leukemia cells in combination with ASNase. ASX-173 slows the growth of OCI-AML2 xenografts in combination with ASNase. ASX-173 is indicated for the study of acute lymphoblastic leukemia, acute myeloid leukemia, colorectal cancer, and other cancers .
Cat. No.: HY-158104
Cat. No.: HY-P2047
CAS No.: 82987-09-5
Synonyms: Antibiotic FR-900201
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