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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
α-CGRP
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "α-CGRP" in MCE Product Catalog:
12
12 Publications Verification
Synonyms: BMS-927711; BHV-3000
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Rimegepant (BMS-927711; BHV-3000) is an orally bioavailable and blood-brain barrier permeable antagonist of CGRP and AMY1 receptors, with a pIC50 of 8.01 and a Ki of 0.027 nM for human CGRP receptors. Rimegepant antagonizes cAMP production induced by αCGRP, βCGRP and amylin at CGRP and AMY1 receptors in humans, rats and mice, as well as at rat AMY3 receptors. Rimegepant can be used in research related to migraine .
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Cardiovascular Disease Metabolic Disease Inflammation/Immunology
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Cardiovascular Disease Metabolic Disease Inflammation/Immunology
6
6 Cited Publications
Cat. No.: HY-P1071
CAS No.: 90954-53-3
Synonyms: Calcitonin gene-related peptide
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6
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5
5 Cited Publications
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MK-3207 is an orally active, highly selective and species-specific CGRP receptor antagonist (for human CGRP receptor: IC50=0.12 nM; Ki=0.024 nM). MK-3207 can be used for migraine studies .
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Synonyms: MK-1602
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Ubrogepant (MK-1602) is an orally active and selective antagonist of calcitonin gene-related peptide receptor (CGRP). Ubrogepant has high affinity for CGRP receptors in human and rhesus monkeys, and can effectively block the cAMP response stimulated by α-CGRP. Ubrogepant can be used in the study of acute migraine .
Cat. No.: HY-P99017
CAS No.: 1644539-04-7
Synonyms: ALD-403
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Cat. No.: HY-P4941
CAS No.: 1816258-61-3
Cat. No.: HY-P4946A
Cat. No.: HY-P4946
CAS No.: 1816258-60-2
Cat. No.: HY-P2601A
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Cat. No.: HY-12366R
CAS No.: 1374248-77-7
Synonyms: MK-1602 (Standard)
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Ubrogepant (Standard) is the analytical standard of Ubrogepant. This product is intended for research and analytical applications. Ubrogepant (MK-1602) is an orally active and selective antagonist of calcitonin gene-related peptide receptor (CGRP). Ubrogepant has high affinity for CGRP receptors in human and rhesus monkeys, and can effectively block the cAMP response stimulated by α-CGRP. Ubrogepant can be used in the study of acute migraine .
Cat. No.: HY-P4714
CAS No.: 124501-79-7
Cat. No.: HY-12366S
Synonyms: MK-1602-d5
Cat. No.: HY-182539
CAS No.: 1202877-06-2
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Cat. No.: HY-15498S
Synonyms: BMS-927711-d4; BHV-3000-d4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
