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α-CGRP (human)

(Synonyms: Calcitonin gene-related peptide)
6 Cited Publications
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Based on 6 publication(s) in Google Scholar

α-CGRP (human) (Calcitonin gene-related peptide) is a regulatory neuropeptide of 37 amino acids. α-CGRP (human) is widely distributed in the central and peripheral nervous system. α-CGRP (human) is a potent vasodilator and has inotropic and chronotropic effects.

For research use only. We do not sell to patients.

  • Purity: 98.86%
  • CAS No.: 90954-53-3
  • Formula: C163H267N51O49S2
  • Molecular Weight:3789.31
  • Storage:

    Sealed storage, away from moisture.

    Powder   -80°C, 2 years , -20°C, 1 year

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • α-CGRP (human) Chemical Structure
    α-CGRP (human) Chemical Structure
  • Experimental Validation Results for α-CGRP (human)
  • Experimental Validation Results for α-CGRP (human)
  • Experimental Validation Results for α-CGRP (human)
  • Experimental Validation Results for α-CGRP (human)
  • Experimental Validation Results for α-CGRP (human)
CAS No.: 90954-53-3
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  • α-CGRP (human) Chemical Structure
    α-CGRP (human) Chemical Structure
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  • 1/16

    α-CGRP (human) purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2025 Dec 24:245:18-29. [Abstract]

    Customer Validation
     Representative Western blot images showing the expression levels of PCNA, phosphorylated CREB (pCREB, Ser133), total CREB, and Gαi3 proteins in MT-2 Treg-like cells transfected with control or RAMP1-specific shRNA and treated with 1 μg/mL CGRP or 50 μM H2O2 for 24 h. β-actin was used as an internal control.

  • 1/16

    α-CGRP (human) purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2025 Dec 24:245:18-29. [Abstract]

    Customer Validation
     Representative CFSE-labeled flow cytometry plots of MT-2 Tregs treated with the indicated concentrations of CGRP (0-3 μg/mL) in the absence (upper panels) or presence (lower panels) of 50 μM H2O2.

  • 1/16

    α-CGRP (human) purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2025 Dec 24:245:18-29. [Abstract]

    Customer Validation
     CGRP (5 μg/mouse/day, s.c. tail, 5 weeks). X-gal staining and immunofluorescence of tail skin sections from each group. Upper panels: X-gal staining visualizing MCs (black arrows); black dashed lines indicate borders between depigmented and normally pigmented areas. Lower panels: Immunofluorescence staining of FOXP3+ Tregs (green) with nuclei labeled by DAPI (blue); white dashed lines denote the dermal-epidermal junction, and white arrows indicate FOXP3+ Tregs.

  • 1/16

    α-CGRP (human) purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2025 Dec 24:245:18-29. [Abstract]

    Customer Validation
     CGRP (5 μg/mouse/day, s.c. tail, 5 weeks). Representative macroscopic and Wood’s lamp images of tail skin from each group.

  • 1/16

    α-CGRP (human) purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2025 Dec 24:245:18-29. [Abstract]

    Customer Validation
     CGRP (10 nM, 72 h) regulates TGF-β and IL-10 production in Tregs. Levels of TGF-β and IL-10 in Treg culture supernatants were measured by ELISA.

  • α-CGRP (human)