3 Results for "

α-helix C

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "α-helix C" in MCE Product Catalog:

Cat. No.: HY-P5726
CAS No.: 302343-01-7
Target:  

Bacterial Antibiotic

Research Areas:  

Infection Cancer

Aurein 1.2 is a C-terminally amidated antimicrobial peptide found in Litoria raniformis. Aurein 1.2 exhibits moderate, broad-spectrum antimicrobial activity against a variety of bacteria, with a MIC of 12-100 μg/mL. Aurein 1.2 forms an amphipathic α-helix with distinct hydrophilic and hydrophobic faces, and may exert antimicrobial and cytotoxic effects on tumor cells by disrupting cell membranes. Aurein 1.2 can be used in studies related to antimicrobial peptides, membrane-active peptides, and tumor cytotoxicity .
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Cat. No.: HY-168886
Target:  

c-Myc

Research Areas:  

Cancer

Anticancer agent 263 (compound 7) is a potent anticancer agent. Anticancer agent 263 binds to the G-quadruplex DNA (G4) sequence 22-mer Pu22, a mimic of c-Myc DNA. Anticancer agent 263 is a structure modulator, showcasing a significant enhancement in protein α-helix formation and the capability to form supramolecular network. Anticancer agent 263 shows no cytotoxicity .
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Cat. No.: HY-111250
CAS No.: 871026-18-5
Target:  

EGFR

Research Areas:  

Cancer

SYR127063 is a potent and selective human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitor with an IC50 of 11 nM. SYR127063 binds to the active site of the HER2 kinase domain in an ATP-competitive manner, thereby preventing the formation of the conserved salt bridge required for kinase activation. SYR127063 can be used in research related to breast cancer, ovarian cancer and gastric cancer .
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