1 Result for "

116180-17-7

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "116180-17-7" in MCE Product Catalog:

Cat. No.: HY-W747548
CAS No.: 116180-17-7
12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. Unstimulated neutrophils metabolize 12(S)-HEPE to 12(S),20-diHEPE, whereas stimulated neutrophils produce 5(S),12(S)-HEPE via the 5-lipoxygenase pathway. The competitive action of 12(S)-HEPE with arachidonic acid as a substrate for 5-LO in the formation of leukotrienes may provide a basis for the anti-inflammatory potential of ω-3 fatty acids.
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