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1231899-06-1

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Anhydroicaritin-3,7-di-O-glucuronide
Anhydroicaritin-3,7-di-O-glucuronide
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Cat. No.: HY-N19800
CAS No.: 1231899-06-1
Category:  

Flavonols Flavonoids Endogenous metabolite

Target:  

Drug Metabolite

Anhydroicaritin-3,7-di-O-glucuronide is a diglucuronide metabolite of icaritin. Anhydroicaritin-3,7-di-O-glucuronide is also a conjugated metabolite derived from prenylated flavonoids of the genus *Epimedium* in rats. In an in vitro microsomal system, Anhydroicaritin-3,7-di-O-glucuronide is mainly catalyzed by UGT1A1 and UGT1A8. Anhydroicaritin-3,7-di-O-glucuronide is generated via sequential glucuronidation at the 3-OH and 7-OH sites of icaritin, or via further conversion from monoglucuronides of icaritin .
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