1 Result for "

1352914-52-3

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1352914-52-3" in MCE Product Catalog:

13
13 Cited Publications
Cat. No.: HY-136453
CAS No.: 1352914-52-3
Purity:  98.38%
Research Areas:  

Cancer

CR-1-31-B is a synthetic rocaglate and a potent eIF4A inhibitor. CR-1-31-B exhibits powerful inhibitory effects over eIF4A by perturbing the interaction between eIF4A and RNA, sequentially impeding initiation during protein synthesis. CR-1-31-B perturbs association of Plasmodium falciparum eIF4A (PfeIF4A) with RNA. CR-1-31-B induces apoptosis of neuroblastoma and gallbladder cancer cells .
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