1 Result for "

1354790-56-9

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1354790-56-9" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-126301
CAS No.: 1354790-56-9
Purity:  99.79%
Target:  

Ferroportin

Research Areas:  

Metabolic Disease

DMT1 blocker 1 is an orally active blocker of divalent metal transporter 1 (DMT1) with an IC50 of 0.64 μM. DMT1 blocker 1 inhibits intestinal cell absorption of non-heme iron, thereby alleviating iron overload by blocking the DMT1 transporter. DMT1 blocker 1 demonstrates significant efficacy in rodent models of acute iron hyperabsorption. DMT1 blocker 1 is useful for studying iron overload disorders such as hereditary hemochromatosis and thalassemia .
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